Abstract
Background: Tuberculosis (TB) a leading cause of death from a single infectious agent, continues to constitute a serious public health challenge in both developed and developing countries. Despite the implementation of the DOTS plan and the subsequent adoption of the End TB strategy, Nigeria continues to fall short of WHO targets especially TB treatment success rate (TSR).
Aim: This study aimed at identifying the trend of TB treatment outcomes and its determinants among patients on TB treatment at the University of Port Harcourt Teaching Hospital Directly Observed Therapy Short-Course (UPTH DOTS) Clinic.
Materials and Method: It was a cross sectional study. Data was collected retrospectively. Information was obtained from the medical records and TB registers at the facility's DOTS clinic covering a five-year period (2016-2020). All patients that were registered in the program whether transferred out or retained were included. The data was retrieved and analysed as needed.
Results: The cumulative results revealed that majority of the subjects were mainly new patients (93.0%), Pulmonary TB (85.2%), and HIV negative patients (65.1%), while the result of the treatment success rate was 61.1% (35.5% cured and 25.6% completed treatment), with treatment failure (0.7%), Lost To Follow Up (LTFU) (16.1%), death (13.4%), transfer out (5.0%), and 3.9% not assessed. However, younger age, being female, employed, having tuberculosis of the lungs (PTB) and being HIV negative were identified as contributors to good treatment outcomes.
Conclusion: The trend in the TB treatment outcome over the 5-year period under review showed that treatment success was highest in 2016 (71.3%) and had a major dip in 2020 (52.1%). This low TSR in 2020 cannot be unconnected with the Corona Virus pandemic which disrupted health and healthcare world-wide that year. Also, the result revealed that younger age, female sex, being employed, PTB, and negative HIV status were the major determinants of favourable TB treatment outcome.
Keywords: Tuberculosis, Treatment outcome, Determinant, DOTS centre, Port Harcourt.
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Corresponding Author
Ojule Inumanye N.
Department of Preventive and Social Medicine, University of Port Harcourt, Port Harcourt, Nigeria
DOI: https://dx.doi.org/10.18535/jmscr/v10i10.26
