Abstract
Primary carcinoma of fallopian tube is a rare malignancy of female genital tract with incidence of 0.3% of gynaecological cancers. Here we are discussing a case series of primary fallopian carcinoma in postmenopausal women. The pre-operative diagnosis of fallopian tube carcinoma is very difficult and usually the first diagnosis is made by pathologist. The frequency of fallopian tube carcinoma is very low that its etiopathogenesis, mode and extent of spread is not well understood. Fallopian tube carcinoma is clinically and histopathologically similar to epithelial ovarian carcinoma so the surgical management and chemotherapy follow the same concept. The early diagnosis of fallopian tube carcinoma lead to better management and improved survival rate. During diagnosis both ovaries and fallopian tubes may appear grossly normal on examination. Lymphatic spread in the fallopian tube carcinoma is of more relevance than ovarian carcinoma. In this series we are discussing presentation, diagnosis, treatment followed in these patients and follow up.
Keywords: Primary fallopian tube carcinoma.
References
- Riska A and Leminen A. Updating on primary fallopian tube carcinoma. Acta Obstetricia et Gynecologica Scandinavica 2007; 86( 12): 1419–1426.
- Mulvany NJ, Arnstein MB, Ryan VA. Prognostic significance of fallopian tube cytology: a study of 99 endometrial malignancies. Pathology 2000; 32:5–9.
- Bhavani C, Babu PVR, Reddy ES, Neeraja M. Bilateral Primary Fallopian Tube Adenocarcinoma – A Rare Case. Int J Med Res Rev 2014;2(4):393-396.
- Pectasides D, Pectasides E, Economopoulos T. Fallopian tube carcinoma. A review. The Oncologist 2006;11:902-912.
- Rosenblatt KA, Weiss NS, Schwartz SM. Incidence of malignant fallopian tube tumors. GynecolOncol 1989;35:236–239.
- Riska A, Leminen A, Pukkala E. Sociodemographic determinants of incidence of primary fallopian tube carcinoma, Finland 1953-97. Int J Cancer2003;104:643–645.
- Ajithkumar TV, Minimole AL, John MM et al. Primary fallopian tubecarcinoma. Obstet GynecolSurv 2005;60:247–252.
- Inal MM, Hanhan M, Pilanci B et al. Fallopian tube malignancies: experience of Social Security Agency Aegean Maternity Hospital. Int J Gynecol Cancer 2004;14:595–599.
- Meng ML, Gan-Gao, Scheng-Sun et al. Diagnosis of primary adenocarcinoma of the fallopian tube. J Cancer Res Clin Oncol 1985;110:136–140.
- Hanton EM, Malkasian GD Jr, Dahlin DC et al. Primary carcinoma of the fallopian tube. Am J Obstet Gynecol 1966;94:832–839.
- Demopoulos RI, Aronov R, Mesia A. Clues to the pathogenesis of fallopian tube carcinoma: a morphological and immunohistochemical case control study. Int J GynecolPathol 2001;20:128–132.
- Rose PG, Shrigley R, Wiesner GL. Germline BRCA2 mutation in a patient with fallopian tube carcinoma: a case report. GynecolOncol 2000;77: 319–320
- Pal A, Rao R, Gupta KB, Dogra P. A rare case of primary carcinoma of fallopian tube (PFTC) The Indian Practioner 2012;65(2): 109-110.
- Agrawal R. Malignancy of fallopian tube. Indian J Pathol Microbiol 2015;58:519-20.
- Stewart SL, Wike JM, Foster SL, and Michaud F. The incidence of primary fallopian tube cancer in the United States. Gynecologic Oncology 2007; 107(3):392–397.
- Jeung IC, Lee YS, Lee HN, Park EK. Primary Carcinoma of the Fallopian Tube: Report of Two Cases with Literature Review Cancer Res Treat 2009;41(2):113-11.
- Ma and Duan: Clinical and survival analysis of 36 cases of primary fallopian tube carcinoma. World Journal of Surgical Oncology 2014 12:311.
- Pfeiffer P, Mogensen H, Amtrup F et al. Primary carcinoma of the fallopian tube. A retrospective study of patients reported to the Danish Cancer Registry in a five-year period. ActaOncol 1989;28:7–11.
- Woolas RP, Smith JHF, Sarharnis P et al. Fallopian tube carcinoma: an under-recognized primary neoplasm. Int J Gynecol Cancer 1997;7:284–288.
- Kol S, Gal D, Friedman M et al. Preoperative diagnosis of fallopian tube carcinoma by transvaginal sonography and CA-125. GynecolOncol 1990;37:129–131.
- Kurjak A, Kupesic S, Sparac V et al. Three-dimensional ultrasonographic and power Doppler characterization of ovarian lesions. Ultrasound Obstet Gynecol 2000;16:365–371.
Corresponding Author
Dr Neha Singh
Junior Resident Department of Obstetrics and Gynaecology, IGMC Shimla, India
DOI: https://dx.doi.org/10.18535/jmscr/v9i11.31
