Abstract
Toxic Epidermal Necrolysis (TEN) is as a rare and a life threatening mucocutaneous condition. Drugs are the leading reported cause of TEN, with the risk of a hypersensitivity reaction mainly in the first few weeks of the drug ingestion. There is strong association between TEN and several drugs, including anti-infectives Sulfonamides, allopurinol, carbamazepine, phenobarbital, nevirapine, lamotrigine, phenytoin, and oxicam-non steroidal anti-inflammatory drugs (NSAIDs).TEN is characterized by widespread keratinocyte apoptosis and sloughing of the skin, erosion of the mucous membranes, painful blistering, and severe systemic disturbance. It involves >30% of total body surface area.
We report a case of 38year old female who developed Toxic epidermal necrolysis after consumption of Allopurinol for joint pain and was being evaluated prognostically with the SCORTEN score.
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Corresponding Author
Dr Jatin Kumar Jain (DNB Medicine Resident)
Department of General Medicine Sarvodaya Hospital and Research Centre, Faridabad, Haryana
DOI: https://dx.doi.org/10.18535/jmscr/v9i11.30
