Abstract
Thyroid dysfunction has a great impact on lipids as well as a number of other cardiovascular risk factors. Hypothyroidism is relatively common and is associated with an unfavorable effect on lipids. Substitution therapy is beneficial for patients with overt hypothyroidism, improving lipid profile. The present study aims to assess the association of hypothyroidism with lipid abnormalities.
References
- Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado thyroid disease prevalence study. Arch Intern Med.2000;160:526–34.
- Stone NJ. Secondary causes of hyperlipidemia. Med Clin North Am.1994;78:117–41.
- Shaikh BA. Clinical features of primary hypothyroidism: a year experience at Chandka medical college, Larkana. Medical Channel. 2008:14 (1) : 72-75.
- Toft A. Hypothyroidism. Med Intern 1989; 8:2596-2600.
- Cappola AR, Ladenson PW. Hypothyroidism and atherosclerosis. Journal of Clinical Endocrinology. Metabolism.2003; 88:2438-2444
- Jawed S, Khawaja TF, Sultan A. Mahmood. Alterations in lipid profile in old age hypothyroid patients. Ann. King Edward Med. Coll. Sep. 2005; 11(3):311-313.
- Nyirenda MJ, Clark DN, Finlayson AR, Read J, Elders A et al. 2005. Thyroid disease and increased cardiovascular risk. Thyroid 15:718-724.
- Kibria KG, Alam MR, Paul HR, Fariduddin M et al. Pattern of Dyslipidemia in Hypothyroid Patients -A cross sectional study. BSMMU J.2013;6(2):156-160.
- Stone NJ. Secondary causes of hyperlipidemia. Med Clin North Am. 1994;78:117-114.
- Dullart RP, Hoogenberg K, Groener JE et al. The activity of cholesterol ester transfer protein is decreased in hypothyroidism: a possible contribution to alterations in high –density lipoproteins. Eur J Clin Invest. 1990;20:581-7.
- Abbas JM, Chakraborty J, Akanji AO, Doi SA. Hypoyhroidism results in small dense LDL independent of IRS traits and hypertriglyceridemia. Endocr J.2008; 55:381-9.
Corresponding Author
Dr Shivbrat Sharma
Junior Resident, MS ENT, DRPGMC Kangra at Tanda (H.P.), India
DOI: https://dx.doi.org/10.18535/jmscr/v9i7.18
