Abstract
Introduction: Malignant melanoma is a type of skin cancer which is arises from the pigment-producing cells - melanocytes. Malignant Melanomas typically occur in the skin but rarely occur in the mouth, intestines or eye (uveal melanoma). Also may occur anywhere on the body. Symptoms of malignant melanoma include a new, unusual growth or a change in an pre-existing mole. Treatment may involve surgical excision, radiation, medication or in some cases, chemotherapy.
Objectives: To document the pattern of clinico-pathological spectrum of malignant melanoma cases at SMS Medical college, Jaipur.
Methods: The present study was a retrospective study conducted in SMS Medical college, department of pathology, Jaipur between 2013 to 2019. During this period total 90 cases received and diagnosed on biopsy.
Results: We received 90 cases in our department with age range from 10 to 86 years. M: F ratio was 1.2:1 with male predominance. Most common age group is 51-60 year. In our study melanoma are predominantly non cutaneous origin (53) like rectum followed by anal canal, nasal-sinonasal, oral cavity and lymph node, followed by cutaneous melanoma (37). Majority of histologic subtype of melanoma are nodular melanoma 17 (45.9%) followed superficial spreading melanoma 13(35.1) then acrolantigeeous 7(18.9). Half (50%) of the excisional biopsies were at Clark’s level III.
Conclusion: Malignant melanoma is aggressive tumor, more common in male then female. Nodular melanoma and superficial spreading was commonest histologic type malignant melanoma in our population.
Keyword: malignant melanoma, nodular, Clark’s level.
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Corresponding Author
Saini Sunita
Assistant Professor, Department of Pathology, Govt SK Medical Collage, Sikar
DOI: https://dx.doi.org/10.18535/jmscr/v9i5.06
