Abstract
Coronavirus disease 2019 (COVID-19) is a pandemic disease spread globally .It is caused by the SARS-COV-2 virus surface spike protein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor, that is expressed in the lung (type 2 alveolar cells), heart, intestinal epithelium, vascular endothelium, and kidneys, providing a mechanism for multi-organ dysfunction. The median incubation period time is 4 to 5 days and 97.5% of patients will exert symptoms within 11.5 days1.Reinfection by COVID 19hs been documented in various parts of the world and is quite alarming. I am reporting a probable case of reinfection by SARS CoV 2 at Government Medical College, Kannur, Kerala.
References
- Clerkin KJ, Fried JA, Raikhelkar J, et al.: COVID-19 and Cardiovascular Disease. 2020; 141(20): 1648–1655
- Li, X. Guan, P. Wu, X. Wang, L. Zhou, Y. Tong, et al. Early transmission dynamics in wuhan, China, of novel coronavirus-infected pneumonia
- Wang, J. Tang, F. WeiUpdated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China J. Med. Virol., 92 (4) (2020), pp. 441-447
- Bosch B.J., van der Zee R., de Haan C.A., Rottier P.J. The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex. 2003;77:8801–8811.
- Li W., Moore M.J., Vasilieva N., Sui J., Wong S.K., Berne M.A., Somasundaran M., Sullivan J.L., Luzuriaga K., Greenough T.C., Choe H., Farzan M. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. 2003;426:450–454.
Corresponding Author
Farha Ahmed Payyanil Karlath
Junior Resident In Internal Medicine, Government Medical College, Kannur, Kerala
DOI: https://dx.doi.org/10.18535/jmscr/v9i3.07
