Abstract
Background: Thrombocytopenia is the second commonest hematological disorder in pregnancy and may result from diverse etiologies.
Aim and Objectives: The study aims to investigate the risk factors, complications and perinatal outcome of pregnancies complicated by thrombocytopenia.
Materials and Methods: A comparative cross sectional study was conducted in Department of obstetrics and Gynaecology, Govt. Medical College, Trivandrum for a period of one year.
Study Population: Include all pregnant women with thrombocytopenia delivering in Department of obstetrics and Gynaecology, Govt. Medical College, Trivandrum, during one year period and comparing them with equal number of antenatal women without thrombocytopenia.
Results: In the present study gestational thrombocytopenia was the commonest cause of thrombocytopenia (40%) followed by severe pre eclampsia and HELLP syndrome.44% delivered preterm due to complicating factors like HELLP, APLA syndrome and abruptio placenta and IUGR. Cesarean rates were higher among cases. Still birth rates (18% v/s 0.6%) and NND (4.8% v/s 0.6%) were high in the study group. Neonatal thrombocytopenia was found in 7 cases (p = 0.007) in thrombocytopenia group.
Conclusion: Gestational thrombocytopenia and ITP had a favorable outcome in the present study. The rare and serious types of thrombocytopenoa like thrombotic thrombocytopenic purpura, APLA syndrome were associated with placental abruption, low APGAR scores and still birth.Careful surveillance help in early detection of complications and timely intervention results in reduced maternal and perinatal mortality.
Keywords: Thrombocytopenia, HELLP, Perinatal outcome.
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Corresponding Author
Dr Sapna Devi D P
Assistant Professor, Dept. of o & G, SAT Hospital, Govt. Medical College, Trivandrum, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i12.24
