Abstract
Introduction: In developing countries like INDIA the prime source of irrevocable visual impairment mainly because of an age related chronic disorder Primary open-angle glaucoma (POAG). It is well known that POAG associated with Type 2 diabetes and hypertension patients.
Aim and Objective: This study aimed to assess the biochemical study in Type-2 Diabetes mellitus primary open angle glaucoma patients as compared to normal controls.
Material and Methods: A total of 200 patients, 100 Type-2 Diabetes mellitus Primary open-angle glaucoma patients with Diabetes and 100 diabetes without POAG from the last one year and 100 normal healthy individuals were chosen as a control group.
Results: The mean values of FBS, HbA1c were significantly increased (P<0.0001) in type -2 Diabetes mellitus Primary open-angle glaucoma cases as compared to normal healthy individuals. Other mean values TC, TG, LDL significantly increased (P<0.0001) in type -2 Diabetes mellitus Primary open-angle glaucoma patient as compared to controls. Whereas the mean value of HDL was significantly decreased in type -2 Diabetes mellitus Primary open-angle glaucoma patient as compared to controls.
Keywords: Primary open-angle glaucoma, FBS, HbA1c, and lipid profile, Type – 2 diabetes mellitus.
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Corresponding Author
Dr Shreya Nigoskar
Professor & HOD, Department of Biochemistry, Index Medical college hospital and research Centre, Malwanchal University, Indore, Madhya Pradesh, India