Abstract
Background: Gastro-Oesophageal Reflux Disease (GERD / GORD) is due to pathological reflux of acidic contents from the stomach to the lower oesophagus. It is one the most common upper gastrointestinal disease. The severity of disease can be assessed by the degree of oesophagitis using the Los Angeles Classification.
Aims and Objectives: To assess the correlation between clinical symptoms and endoscopic findings in patients with GERD.
Materials and Methods: A prospective observational study was conducted on 100 patients aged between 18-60 years presenting with symptoms of regurgitation and heartburn. After obtaining ethical committee approval, and getting informed and signed consent from the patients, Upper Gastrointestinal endoscopy was done and severity of Reflux oesophagitis was observed.
Results: Based on the Los Angeles classification, the severity of the disease assessed was Grade A 23%, Grade B 28%, Grade C 29% and grade D 11%. 9% of the patients did not have any reflux oesophagitis.
Conclusion: Most patients had mild to moderate reflux oesophagitis as per the Los Angeles Classification. Severity of Oesophagitis increased with increase in duration of symptoms.
Keywords: GERD, Los-Angeles Classification, Upper GI scopy, Reflux oesophagitis.
References
- Gyawali CP, Kahrilas PJ, Savarino E, et al. Modern diagnosis of GERD: the Lyon Consensus. Gut 2018;67:1351–1362.
- Kasyap AK, Sah SK, Chaudhary S (2018) Clinical spectrum and risk factors associated with asymptomatic erosive esophagitis as determined by Los Angeles classification: A cross-sectional study. PLoS ONE 13(2): e019273.
- Dent, J. Endoscopic Grading of Reflux Oesophagitis: The Past, Present and Future. Best Pract. Res. Clin. Gastroenterol. 2008, 22, 585–599.
- SS Sami and K Ragunath, The Los Angeles Classification of Gastroesophageal Reflux Disease, Video Journal and Encyclopedia of GI Endoscopy , Volume 1, Issue 1, June 2013, Pages 103-10.
- Akihito Nagahara et al. Clinical feature of asymptomatic reflux esophagitis in patients who underwent upper gastrointestinal endoscopy, Journal of Gastroenterology and Hepatology 27 (2012) Suppl. 3; 53–57.
- Karthik RC et al. Prevalence of gastro esophageal reflux disease among medical students in Chennai, South India, Indian Journal of Forensic and Community Medicine, July-September 2017;4(3):199-203.
- Gunda Jahnavi, Satya Ranjan Patra, Sarah E. Singh, A study of the symptoms of gastro-esophageal reflux disease and associated risk factors among the rural school children of Veleru India. International Journal of Medicine and Public Health Oct-Dec 2013 Vol 3 Issue 4.
- Shobna J. Bhatia et al. Epidemiology and symptom profile of gastroesophageal reflux in the Indian population: Report of the Indian Society of Gastroenterology Task Force Indian Journal of Gastroenterology (May–June 2011) 30(3):118–127.
- Punekar, P. Punekar, Manoj K. Malav, Kalpana Chate. Endoscopic evaluation of gastroesophageal reflux disease. International Journal of Contemporary Medical Research 2018;5(2):B1-B4.
- Raman Muthusamy et al. ASGE Standards of Practice Committee, The role of endoscopy in the management of GERD Gastrointestinal Endoscopy Volume 81, No. 6 : 2015.
Corresponding Author
Dr Palanikumar.B
Junior Resident, Department of General Surgery, Rajah Muthiah Medical College & Hospital, Annamalai University, Tamil Nadu, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i11.37
