Abstract
Brugada syndrome is an characteristic electrocardiogram finding which indicates risk of arrhythmia and sudden cardiac arrest leading to death. A characteristic downsloping st elevation with coved morphology and t wave inversion in V1-V3 is indicative of brugada syndrome and is often unmasked by fever and certain drugs. Here we present a case of 56 year old male in without any cardiac complaints in whom brugada syndrome was unmasked by fever due to urinary tract infection and treating the underlying infection and fever caused the electrocardiogram changes to subside.
Keywords: brugada syndrome, brugada sign, fever, arrhythmia, sudden cardiac death.
References
- Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992; 20:1391–1396.
- Wilde AA, Antzelevitch C, Borggrefe M, BrugadaJ, Brugada R, Brugada P, Corrado D, Hauer RN, Kass RS, Nademanee K, Priori SG, Towbin JA. Proposed diagnostic criteria for the Brugada syndrome: consensus report. Circulation 2002; 106:2514–2519.
- Conte G, Sieira J, Ciconte G, de Asmundis C, Chierchia G-B, Baltogiannis G, Di Giovanni G, La Meir M, Wellens F, Czapla J, Wauters K, Levinstein, Saitoh Y, IrfanG, Julià J, Pappaert G, Brugada Implantable cardioverter-defibrillator therapy in Brugada syndrome: a 20-year single-center experience. J Am Coll Cardiol 2015;65:879–888.
- Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada P, Potenza D, et al. Genetic basis and molecular mechanisms for idiopathic ventricular fibrillation, Nature, 1998, vol. 392.
- Antzelevitch C, Brugada R. Fever and Brugada syndrome. Pacing Clin Electrophysiol. 2002;25:1537–1539.
- Junttila MJ, Gonzalez M, Lizotte E, Benito B, Vernooy K, Sarkozy A, Huikuri HV, Brugada P, Brugada J, Brugada R. Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation. 2008;117:1890–1893.
- Sarkozy A, Chierchia GB, Paparella G, Boussy T, de AC, Roos M, Henkens S, Kaufman L, Buyl R, Brugada R, Brugada J, Brugada P. Inferior and lateral electrocardiographic repolarization abnormalities in Brugada syndrome. Circ Arrhythm Electrophysiol. 2009; 2:154–161.
- Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, et al. Brugada syndrome: report of the second consensus conference. Heart Rhythm 2005;2:429–40.
- Eckardt L, Probst V, Smits JP, Bahr ES, Wolpert C, Schimpf R, et al. Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome. Circulation 2005;111:257–63.
- Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. 6th ed. Philadelphia: Saunders Elsevier; 2014.
Corresponding Author
Dr Ram Arvind V
Post Graduate Residents, Department of General Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry-605107, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i9.08
