Abstract
Sub-acute combined degeneration of spinal cord is a common manifestation of Vitamin B12 deficiency in the age group of more than 40 years. But it has been rarely reported in paediatric age group. We hereby illustrating a case of 17 years male adolescent diagnosed to have this neurological manifestation of Vitamin B12 deficiency. Patient was started on parenteral Vitamin B12 followed by oral folic acid and iron supplementation and showed gradual symptomatic improvement.
Keywords: Neurological manifestations of B12 deficiency, Sub-acute combined degeneration of spinal cord, Demyelination, non compressive myelopathy.
References
- Srikanth SG, Jayakumar PN, Vasudev MK, Taly AB, Chandrashekhar HS. MRI in Subacute Combined Degeneration of Spinal Cord: A case report and review of literature. Neurology India, 2002; 50: 310 - 312.
- Beal MF, Martin JB. Nutritional and Metabolic diseases of the Nervous system. In Harrison's principles of Internal Medicine. 14th edition, 1998: 2456. Mc Graw Hill Book Co, Singapore.
- A. Singer, C. Lazaridis, S. P.Nations, and G. I.Wolfe, “Reversible nitrous oxide-induced myeloneuropathy with pernicious anemia: case report and literature review,” Muscle and Nerve, vol.37, no.1, pp.125–129, 2008.
- Wadia RS, Bandishri S, Kharche Vit.B12 and folate deficiency; incidence and clinical features. Neurol.India. 2000; 48 (4): 302-4.
- Ravina B, Loevner LA, Bank W: MR findings in subacute combined degeneration of the spinal cord: a case of reversible cervical myelopathy. AJR Am J Roentgenol. 2000, 174: 863-865.
- Berlit, A. Ringelstein, and T. Liebig, “Spinal MRI precedes clinical improvement in subacute combined degeneration with B12 deficiency,” Neurology, vol.63, no.3, article592, 2004.
Corresponding Author
Nishant Acharya
Department of Paediatrics, Dr. RKGMC Hamirpur (H.P), India
DOI: https://dx.doi.org/10.18535/jmscr/v8i6.96
