Abstract
Nevus sebaceous is a hamartoma of the skin and its adnexa. Cerebriform nevus sebaceous is a morphological variant commonly seen in newborn infants over the scalp as large, pedunculated or verrucous, hairless plaques. Most lesions are isolated but some may be associated with other systemic abnormalities including CNS, cardiovascular, ocular and urological involvement. Most lesions are benign but there is a very small chance of malignant transformation especially when they grow during puberty and hence biopsy should be done in all cases and if possible complete excision.
We describe a newborn infant with cerebriform nevus sebaceous of the scalp with no other systemic abnormalities. The lesion was excised completely and biopsy showed no evidence of malignant potential.
Keywords: Nevus, hamartoma, cerebriform nevus, neonate
References
- Terenzi V, Indrizzi E, Buonaccorsi S, Leonardi A, Pellacchia V, Fini G. Nevus sebaceus of Jadassohn. J Craniofac Surg. 2006; 17: 1234-1239.
- Saedi T, Cetas J, Chang R, Krol A, Selden NR. Newborn with sebaceous nevus of jadassohn presenting as exophytic scalp lesion. Pediatr Neurosurg. 2008; 44: 144-147.
- West C, Narahari S, Kwatra S, Feldman S. Autosomal dominant transmission of nevus sebaceous of Jadassohn. Dermatol Online J. 2012; 18: 17.
- Chi SG, Kim JY, Kim HY, Lee SJ, Kim do W, Lee WJ. Multiple nevus sebaceous occurring on the scalp and on the contralateral side of the face. Ann Dermatol. 2011; 23: 389-391.
- Ramesh A, Murugusundaram S, Vittel K, Kumar S, Janaki VR, Boopalraj JM: Cerebriform sebaceous nevus. Int J Dermatol 1997;37:220.
- Valerio E, Mardegan V, Zanella C, Gaio P, Cutrone M: Cerebriform nevus sebaceous in neonate. J Pediatr 2014;164:665–666.
- Menascu S, Donner EJ: Linear nevus sebaceous syndrome: case reports and review of the literature. Pediatr Neurol 2008;38:207–210.
- Altaykan A, Ersoy-Evans S, Erkin G, Ozkaya O. Basal cell carcinoma arising in nevus sebaceous during childhood. Pediatr Dermatol. 2008; 25: 616-619.
- Simi CM, Rajalakshmi T, Correa M. Clinicopathologic analysis of 21 cases of nevus sebaceus: a retrospective study. Indian J Dermatol Venereol Leprol. 2008; 74: 625-627.
- Idriss MH, Elston DM. Secondary neoplasms associated with nevus sebaceus of Jadassohn: a study of 707 cases. J Am Acad Dermatol. 2014; 70: 332-337.
Corresponding Author
Meghmala Sadhukhan
Junior Consultant, Department of Paediatrics & Neonatology, AMRI Hospitals, Bhubaneswar, India