Abstract
High blood pressure is ranked as the 3rd most important risk factors for attributable burden of disease in South Asia. Hypertension is responsible for 57% of stroke deaths in India. Cardiovascular disease will be the largest cause of death and disability in India by 2020. This study aim to analyze the quality of life and medication adherence for hypertensive patients attended tertiary care hospital.
Methods: We conducted prospective observational study on hypertensive patients by use Quality of life and medication adherence questionnaires (minichal Brazil and hill bone complains scale).
Results: The study included 230 populations. The average age group was 65 years old. Out of 230 patients only 30% of patients came for follow-up and their QOL and medication adherence was compared. The quality of life and medication adherence was increase when compared with previous and P value {<0.0001}.
Conclusion: The correlation between quality of life and medication adherence was inverse and statistically significant highlighting that greater adherence implies better quality of life. The involvement of clinical pharmacist in providing patient education regarding his condition and medication and life style modification improves patient medication adherence & quality of life.
References
- Yurdakul S, Aytekin S. Hypertension in women. Arch Turkish Soc Cardiol. 2010;38(1):25–31.
- Abaci A. The current status of cardiovascular risk factors in Turkey. Arch Turkish Soc Cardiol. 2011; 39(4):1–5.
- Dorairaj Prabhakaran, et, al. Prevalence and Incidence of Hypertension: Results from a representative cohort of over 16,000 adults in three cities of South Asia. Indian Heart Journal. July – August 2017, Volume 69 ;( 4):434-41.
- GBD Compare | IHME Viz Hub. Global; both series, all ages, 2017, DALYS. Available from: https://vizhub.healthdata.org/gbd-compare/#, accessed on February 27, 2019.
- Gupta R, Gaur K, S Ram CV. Emerging trends in hypertension epidemiology in India. J Hum Hypertens2018; doi:10.1038/s41371-018-0117-3.
- Raghupathy Anchala, et.al. Hypertension in India: A systemic review and metaanalysis of prevalence, awareness, and control of Journal of Hypertension. 2014 June 32(6), 1170-77.
- Srinivas et.al. Prevalence of prehypertension in adult population of rural Andhra Pradesh. Asian Journal of Biomedical and Pharmaceutical Science. 2013, vol.3 (23);45.
- Oza BB, et, al. Health related quality of life in hypertensive patients in a tertiary care teaching hospital. 2014..
- G Parthasarathi et, A Textbook of Clinical Pharmacy Practice, essential concepts and skills. Ch. 6,55-63.
- Burnier M, Wuerzner G, Struijker-Boudier H, Urquhart J. Measuring, analyzing, and managing drug adherence in resistant hypertension. Hypertension. 2013;62:218–25.
- van Veen WA. Treatment adherence in hypertension: problems and research. J R Coll Gen Pract Occas Pap. 1980;(12):22–5.
- Tadesse M, Eyob A, Akshay S, Asim A. Nonadherence to antihypertensive drugs. A systematic review and meta-analysis. Medicine. 2017;96:e5647.
- Tomaszewski, M., et al., High rates of nonadherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry (HP LC-MS/MS) urine analysis. Heart, 2014: p. heartjnl-2013-305063.
- Ana Paula Ferreira Maciel, et, al. Quality of life and Medication Adherence in Hypertension Patients. October 2016, Vol. 29(5).
- Alhaddad IA et, al. Treatment adherence and quality of life in patients on Antihypertensive medications in a Middle Eastern, Dove medical press, 27 October 2016 Volume 2016:12 Pages 407—413.
- Anup Bhusal, et, al. Assessment of medication adherence among Hypertensive Patients: a cross sectional study. International Journal of Basic and Clinical Pharmacology. July-August 2016, Vol. 5(4); 1606-1612.
Corresponding Author
Dr K. Mahitha Reddy, Pharm.D
Dept of Clinical Pharmacy, Chalmeda Anandrao Institute of Institute of Medical Sciences & Vaageswari College of Pharmacy, Telangana, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.71
