Title: Association of Tuberculosis with Other Infections in Post Renal Transplant Recipients- A Retrospective Study
Authors: Karan S. Thakur, Deepesh B Kenwar, Ashish Sharma, Sarabpreet Singh, Purnima Patial
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.57
Abstract
The number of Renal Transplantations is increasing among developing nations. Tuberculosis is a big health problem in endemic countries. TB is a leading cause of morbidity and mortality in endemic countries and more common in kidney transplant patients. Renal transplant recipients are at risk for reactivation of latent Mycobacterium tuberculosis infection and primary infections. So relative risk of TB is high in organ transplantation. Other infections for example CMV, Pneumocystis carinni downgrade host immunity and may activate occult TB. Most of the cases of TB and other infections occur in the initial months of transplant surgery and during most intense period of immunosuppressant drugs. Risk of TB and associated infections depends on geographical regions also. TB is a barrier in successful long-term outcome in renal transplant. Thus this study tried to determine the association of post Renal Transplant TB with various co-infections.
Keywords: Renal Transplant, TB-Tuberculosis, CKD-Chronic Kidney disease.