Abstract
Asthma and allergy often occur together. People with allergic rhinitis, atopic eczema, food allergy and those who have asthma running in the family are at risk of developing asthma. Allergy is the most common cause of triggering asthma.
Bronchial asthma and rhinosinusitis are common respiratory diseases that often coexist. Furthermore and of considerable interest is the possibility that severity of asthma is influenced by the upper airway diseases. The influence and interaction between asthma and rhinitis exist with chronic rhinosinusitis, allergic rhinitis, viral and Bacterial respiratory tract infection. These observations raise the possibility, that events in the upper respiratory tract can influence lower respiratory tract. It’s now being appreciated the concept of one airway and one disease, also known as Allergic rhinitis and its impact on asthma (ARIA). We have conducted a study to assess Atopy by measuring serum IgE levels & esinophils in asthma and rhinosinusitis patients and comparing the two groups.
Keywords: Atopy, Allergic rhinitis, Asthma, Rhinosinusitis, serum IgE, Eosinophils.
References
- Pawankar R, Canonica GW, ST Holgate ST, Lockey RF, Blaiss M. The WAO White Book on Allergy (Update. 2013).
- Global Initiation of Asthma (GINA 2017update).
- Fokkens W, Lund V, Bachert C, Clement P, Hellings P, Holmstrom M, et al. EAACI position paper on rhinosinusitis and nasal polyps. Allergy 2005;60:583-601.
- Van Zele T, Claeys S, Gevaert P, Van Maele G, Holtappels G, Van Cauwenberge P, et al. Differentiation of chronic sinus diseases by measurement of inflammatory markers. Allergy 2006;61:1280-9.
- Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol 2004;113:832‐6.
- Annesi-Maesano I. Epidemiological evidence of the occurrence
of rhinitis and sinusitis in asthmatics. Allergy 1999;54 (Suppl
57):7-13.
- Slavin RG, Sinusitis in adults and its relation to allergic rhi- nitis, asthma and nasal polyps. J All Clin Immunol 1988;82: 950-6.
- S. K. Jindal; Indian Study on Epidemiology of Asthma, Respiratory Symptoms and Chronic Bronchitis (INSEARCH) A Multi‐Centre Study (2006‐2009)
- Farida Agha, Agha Sadaruddin, S. Mohsin Ali (PMRC Central Research Centre, Islamabad. Serum IgE Levels in Patients with Allergic Problems and Healthy Subjects Pages with reference to book, From 166 To 169.
- Bachert & N. Zhang; Chronic rhinosinusitis and asthma: novel underst-anding of the role of IgE ‘above atopy’ doi: 10.1111/j.1365-2796.2012.02559.
- Jarvis D, Newson R, Lotvall J, et al. Asthma in adults and its associ- ation with chronic rhinosinusitis: The GA2LEN survey in Europe. Allergy 67:91–98, 2012. 28
- Lynn E. Katz Blood Eosinophil Count Is a Useful Biomarker to Identify Patients with Severe Eosinophilic Asthma February 15,2014.
Corresponding Author
Dr Shahzad Hussain Arastu
Assistant Professor of Pulmonology, Shadan Institute of Medical Science, Hyderabad, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.52
