Abstract
Rheumatoid arthritis (RA) is the most common chronic symmetric polyarthritis characterized by erosive arthritis, joint destruction and a variety of extraarticular manifestations. Insights gained by a wealth of basic and clinical research over the past two decades have revolutionized the contemporary paradigms for the diagnosis and management of RA.A clinical state defined as low disease activity or remission is the optimal goal of therapy. Composite indices, such as the Disease Activity Score -28 or DAS28 is very useful in practise. Vitamin D has an immunomodulatory role in RA and its reduced intake is associated with increased disease activity. High inflammatory burden in RA contributes to cardiovascular morbidity and there’s reduced levels of High-Density Lipoprotein (HDL) cholesterol. Hence, Serum Vitamin D & HDL level can serve as useful markers of disease activity in RA.
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Corresponding Author
Dr Cankatika Choudhury
MD, Department of Medicine, R.G. Kar Medical College & Hospital, Kolkata
DOI: https://dx.doi.org/10.18535/jmscr/v8i3.71
