Abstract
Objective: In this study, we aim to determine whether patients with sudden SNHL in North India, had an elevated Mean platelet volume (MPV), platelet count (PC) and platelet distribution width (PDW).
Study Design: Cross- sectional observation study
Setting: PGIMER, Dr Ram Manohar Lohia Hospital, New Delhi
Subjects and Methods: In this study, a group of 30 patients and 30 healthy subjects were taken as controls. Blood samples were drawn immediately on admission. The platelet parameters were analysed in the Medonic M series haematology cell counter. Comparisons of the blood indices were made between the two groups. Quantitative variables were compared using Unpaired t-test /Mann Whitney test (when data sets were not normally distributed) between the two groups.
Qualitative variables were correlated using Chi Square test/Fischer’s exact test. A p value of < 0.05 was considered statistically significant.
Results: Although the MPV, PDW and PC were marginally higher in the cases compared to the control group, a significant difference (p< 0.05) was not observed between the two groups. The mean platelet volume showed a p value of 0.197, the platelet count had a p value of 0.433 and the platelet distribution width revealed a p value of 0.67.
Conclusion: Hence, the mean platelet volume and other platelet parameters are not associating factors in the occurrence of sudden sensorineural hearing loss.
Keywords: Mean platelet volume, platelet parameters, sudden sensorineural hearing loss.
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Corresponding Author
Ibadaiamon Mawroh
Department of Otorhinolaryngology , Head and Neck surgery, PGIMER , Dr Ram Manohar Lohia Hospital, New Delhi -110001, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i3.70
