Abstract
Objective: The aim of present study was to evaluate the role of FNAC as a diagnostic tool in a cases of lymphadenopathy.
Material and Methods: A total 124 patients with palpable lymph nodes of different age groups of both sexes were referred for FNAC in the department of pathology, Sri Krishna Medical College, Muzaffarpur during the period of November 2018 to October 2019. Among 124 cases, 6 cases were excluded from the study due to inadequate materials, hence we analysed 118 cases only.
Result: Male to female ratio was 1.14:1. Tubercular lymphadenitis was the commonest lesions in 45 (38.13%) cases followed by reactive hyperplasia in 40 (33.13%) cases. Among the neoplastic lesion lymphoma (Hodgkin’s and Non hodgkin’s) was the commonest pathological findings in 10 (8.47%) cases followed by metastasis in 5 (4.23%) cases.
Conclusion: Fine needle aspiration cytology is a primary diagnostic tool in the evaluation of lymph node lesions due to its low cost, simplicity and minimal invasiveness.
Keyword: Lymph node, FNAC, tubercular lymphadenitis.
References
- Orell SR, Sterrett GF. Fine Needle Aspiration Cytology. 5th Edinburgh : Churchill Livingstone ; 2012
- Steel BL, Schwartz MR, Ramzy I – Fine needle aspiration biopsy in the diagnosis of lymphadenopathy in 1,103 patients: role, limitations, and analysis of diagnostic pitfalls. Acta Cytol 1995; 39: 76-81
- Nasuti JF, Yu G, Boudousquie A, Gupta P – Diagnostic value of lymph node fine needle aspiration cytology: an institutional experience of 387 cases observed over a 5-year period. Cytopathology 2000; 11: 18-31
- Gupta RK, Naran S, Lallu S, Fauck R – The diagnostic value of fine needle aspiration cytology (FNAC) in the assessment of palpable supraclavicular lymph nodes: a study of 218 cases. Cytopathology 2003; 14: 201-7
- Das DK – Lymph nodes. In: Bibbo M, editor. Comprehensive Cytopathology. 2nd Philadelphia: WB Saunders, 1997: 703-29.
- Ajmall F, Imran A. Comparison of FNAC vs excision biopsy for suspected tuberculous cervical lymphadenopathy. Ann King Edward Med Coll 2013; 9:216-8
- Nasuti JF, Mehrotra R, Gupta PK. Diagnostic value of fine needle aspiration in Supraclavicular lymphadenopathy : a study of 106 patients and review of literature. Diagn Cytopathol. 2001; 25:351-5.
- Garbyal RS, Basu D, Roy S, Kumar P. Cryptococcal lymphadenitis: Report of a case with fine needle aspiration cytology. Acta Cytol 2005; 49: 58-60
- F. Lioe, H. Elliott, D.C. Allen and R. A.J. Spence. The role of fine needle aspiration cytology in the investigation of superficial lymphadenopathy : uses and limitations of the technique. Cytopathology 1999 ; 10 : 291-297.
- Ruchi Khajuria, K.C. Goswami, K. Singh, V.K. Dubey. Pattern of lymphadenopathy on Fine Needle Aspiration Cytology in Jammu ; JK science 2006; 8(3) : 23-28
- Sumit Mitra, Sucandra Ray, Pradip K Mitra. Fine needle aspiration cytology of supraclavicular lymph nodes : Our experience over a three-year period. Journal of Cytology 2011 ; 28(3) : 52-57
- Pandit A A, Candes FP, Khub Chandini SR. Fine needle aspiration cytology of lymph nodes. Journal of postgraduate medicine : 1987 ; 33(3) : 134-136
- Hirachand S, Lakhey M, Akhter J, Thapa B. Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu University Medical Journal 2009 ; 7(26) : 139 - 142
- Bailey TM, Akhtar M, Ali MA. Fine needle aspiration biopsy in the diagnosis of tuberculosis. Acta Cytol. 1985;29:732-736.
- Radhika S, Gupta SK, Chakrabarti A, et al. Role of culture for mycobacteria in fine needle aspiration diagnosis of tuberculous lymphadenopathy. Diagn Cytopathol. 1989: 5 : 260-262
Corresponding Author
Dr Pankaj K Patel
Associate professor, Department of Pathology, S. K. Medical College, Muzaffarpur, India