Abstract
Duodenal GISTs are quite a rare phenomenon and their management is very tricky depending on the part of the duodenum from where it arises. We report a case of 68 year old male from West Bengal, India presenting with features of sealed off perforation with a retroperitoneal collection and finally diagnosed with High Grade GIST from duodenum (D1-D2), Spindle cell Type, T4NxM0. Patient underwent Wedge Resection of the tumour followed by Imatinib therapy.
Keywords: GIST, Duodenal Gist , Perforation.
References
- Akahoshi, Kazuya et al. “Current clinical management of gastrointestinal stromal tumor.” World journal of gastroentero-logy vol. 24,26 (2018): 2806-2817.
- Panbude S, Ankathi S, Ramaswamy A, Saklani A. Gastrointestinal Stromal Tumor (GIST) from esophagus to anorectum – diagnosis, response evaluation and surveillance on computed tomography (CT) scan. Indian J RadiolImaging. 2019 Apr 1;29(2):133–40.
- Gastrointestinal stromal tumour. Joensuu H, Hohenberger P, Corless CL Lancet. 2013 Sep 14; 382(9896):973-83
- Beham A, Schaefer I-M, Cameron S, von Hammerstein K, Füzesi L, Ramadori G, et al. Duodenal GIST: a single center experience. Int J Colorectal Dis 2013
- Huang Y, Chen G, Lin L, Jin X, Kang M, Zhang Y, et al. Resection of GIST in the duodenum and proximal jejunum: A  retrospective analysis of outcomes. Eur J Surg Oncol. 2019 Oct 1;45(10):1950–6.
- Hong L, Zhang T, Lin Y, Fan R, Zhang M, Cheng M, et al. Prognostic Analysis of Duodenal Gastrointestinal Stromal Tumors. De Palma GD, editor. Gastroenterol Res Pract .2018;2018:4812703.
- Parab TM, De Rogatis MJ, Boaz AM, Grasso SA, Issack PS, Duarte DA, et al. Gastrointestinal stromal tumors: a comprehensive review. J Gastrointest Oncol. 2019 Feb;10(1):144–54.
- Duffaud F, Le Cesne A. Recent advances in managing gastrointestinal stromal tumor. F1000 Research . 2017 Sep 14;6:1689.
- Call JW, Wang Y, Montoya D, Scherzer NJ, Heinrich MC. Survival in advanced GIST has improved over time and correlates with increased access to post-imatinib tyrosine kinase inhibitors: results from Life Raft Group Registry. Clin Sarcoma Res.
Corresponding Author
Aditya Sivaram S
Dept of General Surgery, Sri Ramachandra Institute for Higher Education and Research, Chennai, India
DOI: https://dx.doi.org/10.18535/jmscr/v8i3.35
