Title: Comparison of preloading versus coloading with crystalloid for elective caesarean section done under low dose spinal anaesthesia – A double blind randomised trial
Authors: Dr Ankita Chandel, Dr Nisha Sharma, Dr Manjit Singh Kanwar
DOI: https://dx.doi.org/10.18535/jmscr/v8i1.124
Abstract
Background: Spinal anaesthesia is now an established technique for lower segment caesarean section (LSCS) but is associated with maternal hypotension. We intended to compare the use of preloading vscoloading with crystalloid for prevention of same.
Methods: Fifty parturients with American Society of Anesthesiologists’ physical status 1 or 2 undergoing elective LSCS were recruited. Twenty five patients in group P (n =25) and group C (n =25) received 15 mL/kg of ringer lactate 20 minute before spinal anaesthesia and just after spinal anaesthesia respectively in both groups. Blood pressure and heart rate were recorded at 1 min interval starting 1 min after intrathecal injection till the first 10 min, every 5 min till the next 20 min and every 10 min thereafter till the end of the surgery. Data was tabulated using Microsoft excel (2010) and analyzed using the SPSS (version 8) software. Student's t-test was used for quantitative data and the Chi square test for qualitative data.
Results: The minimum mean systolic blood pressure (SBP) values recorded in the two groups were 90 ± 12.5 mm Hg in group P and 100 ± 9.5 mm Hg in group C (P = 0.043) at 7th and 6th minute respectively. The mean number of doses of mephentermine were more in group P (1.56±0.234) compared to group C (0.75±0.452). (P< 0.0001).
Conclusion: Coloading provides a better alternative than preloading for prevention of maternal hypotension secondary to spinal anaesthesia given for caesarean section.
