Abstract
Background and Objective: Iron deficiency anemia is the most common form of anemia in pregnancy and also the most common nutritional disorder. Anemia during pregnancy is a significant concern because of its association with adverse pregnancy outcomes. According to WHO, the prevalence of iron deficiency anemia in pregnancy is 40.1%. The objective of this study is to compare the efficacy of oral versus parenteral iron therapy in the treatment of anemic pregnant women.
Materials and Methods: It was a randomized controlled clinical trial conducted in Regional Institute of Medical Sciences. A total of 50 anemic pregnant women meeting the inclusion criteria and giving the informed consent were taken into the study. Those are in the oral group(25), taken two 100 mg ferrous ascorbate and in parenteral (iron sucrose) group(25), was administered 200mg elemental iron in 200ml of normal saline. Results were interpreted after taking Hb % and Serum ferritin levels after 14 and 28 days of administration.
Results: The haemoglobin in oral group after 14 and 28 days of treatment were (9.19±0.49) and (10.76±0.49) and for intravenous group (9.64± 0.45) and (11.41± 0.51) respectively. Serum ferritin values after 28 days of oral and intravenous treatment are (50.68± 2.64) and (60.92± 6.90) respectively. So the p value < 0.001, which was significant.
Conclusion: Intravenous iron sucrose was well tolerated and good patient complaint with comparable efficacy than oral ferrous ascorbate in treating anemic pregnant women.
Keywords: Iron deficiency anemia in pregnant women, iron sucrose, ferrous ascorbate,
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Corresponding Author
Usharani Akoijam
Department of Obstetrics and Gynecology, Regional Institute of Medical Sciences, Imphal, Manipur
DOI: https://dx.doi.org/10.18535/jmscr/v8i1.92
