Abstract
Introduction: Non‑neoplastic and neoplastic cervical lesions are seen among women of all age groups but are more common in sexually active women. In developing countries, there is a lack of effective screening programs and vaccination due to which there is increased risk of cervical cancer.
Methods: A retrospective histopathological analysis of 690 cases of cervical lesions were undertaken in the department of pathology over a period of 5 year at Government Medical College haldwani, Uttarakhand.
Results: Out of 690 cases, Non-neoplastic lesion were seen in 570 cases (82.4%) while neoplastic lesion were seen in 120 cases (17.6%). The most commonly affected age group was 41-50 yr. Among non-neoplastic lesion most common histological finding was chronic cervicitis in premenopausal age group and squamous metaplasia in postmenopausal age group. Among neoplastic lesion, non-Keratinising squamous cell carcinoma was the most common finding in both premenopausal and postmenopausal age group followed by keratinising squamous cell carcinoma.
Keywords: Cervicitis, Squamous metaplasia.
References
- Forae G, Nwachokor F. Morphological spectrum of non-neoplastic lesions of the uterine cervix in Warri, South-South, Nigeria. Niger J Clin Pract. 2013;16(4):429.
- Mukesh S, Arul Ponni T, Nirmala S, Janaki M. Aggressive approach in a case of cancer cervix with uremia. Indian J Palliat Care. 2010;16(1):52.
- Bagde S, Gupta R, Ganguly S, Bhardwaj A, Jogi S. SPECTRUM OF CERVICAL LESIONS IN CIMS, BILASPUR: A 5 YEAR RETROSPECTIVE STUDY OF 215 CASES IN A TERTIARY HOSPITAL OF CENTRAL INDIA. jebmh. 2015 Oct 19;2(42):7505–10.
- Faridi R, Zahra A, Khan K, Idrees M. Oncogenic potential of Human Papillomavirus (HPV) and its relation with cervical cancer. Virol J. 2011;8(1):269.
- Keshinro SO, Nwafor CC, Oshun P. HISTOLOGIC ANALYSIS OF GYNAECOLOGIC LESIONS IN NIGERIANS. East African Medical Journal. 2015;8.
- Rajendiran S, Gopalan U, Karnaboopathy R. Evaluation of histopathology of cervix in women with unhealthy cervix. Int J Reprod Contracept Obstet Gynecol. 2017 Feb 19;6(3):842.
- Clinico-Pathological Study of Non-Neoplastic Lesions of Uterine Cervix with their Histopathological Categorization. 2013;4(2):5.
- Poste P, Patil A, Andola SK. Incidence of Non-Neoplastic Cervical Pathologies Recorded at a Medical College. :12.
- Pallipady A, Illanthody S, Vaidya R, Ahmed Z, Suvarna R, Metkar G. A Clinico-Morphological Spectrum of the Non Neoplastic Lesions of the Uterine Cervix at AJ Hospital, Mangalore. Journal of Clinical and Diagnostic Research. 2011;5:5.
- Jones MA, Young RH. Atypical oxyphilic metaplasia of the endocervical epithelium: a report of six cases. Int J GynecolPathol. 1997 Apr;16(2):99–102.
- D P, AArathiC. Histopathological Spectrum of Non-Neoplastic Uterine Cervical Lesions in a Tertiary Care Centre. APALM. 2017 May 28;4(3):A303–9.
- Reddy S, Rani M, Rao K. Clinico-histopathologic study of nonneoplastic uterine cervical lesions. Int J Med Sci Public Health. 2016;5(8):1536.
Corresponding Author
Dr Usha Joshi
Associate Professor, Department of Pathology, Government Medical College Haldwani, India