Abstract
Background: Diabetes Mellitus (DM) is a metabolic disease of modern civilization. It is associated with reduced life expectancy, significant morbidity due to specific diabetes related microvascular complications, increased risk of macrovascular complications and diminished quality of life. Urinary tract infection (UTI) is a common infection observed in diabetic patients. DM alters the genitourinary system where UTI can cause severe complications ranging from dysuria, organ damage and even death due to complicated UTI. Current study was carried out to evaluate UTI pathogens its association with clinical profile and susceptibility patterns to antimicrobials among diabetic patients.
Materials and Method: A one-year cross sectional, descriptive study was carried out in tertiary care hospital. Total 60 patients of DM with UTI were included based on inclusion criteria. Research tool consisted of questionnaire, clinical examination and investigations. Pus cells grading into categories were taken as dependent variables and clinical parameters (duration of DM, glycosylated hemoglobin levels, past episodes of UTI, past catheterization) as independent variables.
Results: Incidence of UTI in D.M. was mostly seen in women and above 50 years of age. Fever was the commonest symptom, UTI most common in patients with past history of diabetes of less than 10 years duration. Most common organism isolated in UTI was E. coli. Gram negative bacilli were sensitive to imipenem, gentamycin, nitrofurantoin, and Gram-positive cocci were sensitive to vancomycin, linezolid, tetracycline in most of the patients. Poor Glycemic control was significantly associated with more pus cells in urine.
Keywords: Diabetes Mellitus, Urinary tract infection, Bacteriology, Antimicrobial sensitivity.
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Corresponding Author
Dr Priya A. Warbhe
Assistant Professor, Department of Community Medicine, First Floor, Near Blood bank, Dr. PDMMC, Amravati, Maharashtra, India
DOI: https://dx.doi.org/10.18535/jmscr/v7i12.04
