Abstract
Background: Long after completion of tuberculosis (TB) therapy, many patients with previous pulmonary tuberculosis (PTB) continue to experience respiratory symptoms, frequently resulting in Ventilatory defect, deterioration in quality of life and exercise capacity.
Objective: To describe the health of patients with a history of adequately treated microbiologically positive Pulmonary Tuberculosis Patients.
Methods: A cross-sectional study that was conducted in349 successfully treated Pulmonary tuberculosis patients of age >18 years who were put on ATT between 1stQ of 2016 TO 4th Q of 2016. Patients with current culture and AFB-positive TB were excluded. Data was collected by demographic details, respiratory symptoms, comorbidities and chest radiography findings after TB treatment. Lung function impairment was defined by the presence of at least one of these three abnormalities. Radiographic abnormalities, effect on quality of life and exercise capacity were assessed by chest X-ray, St George’s questionnaire and 6 minute walk test.
Results: Of a total of 160 participants included in the study, 55.68% were male. The mean age of participants was 35.36 years. Radiological abnormality was detected in only 84% patients. Out of finally selected 160 successfully treated pulmonary tuberculosis patients pulmonary impairment was observed in 88(55%). Mixed pattern was the most common ventilatory defect (45.45%) followed by pure obstruction (30.68%).Mean 6 minute walk distance was 334.39(137.07) meter and total SGRO score was 53.34(21.56).
Conclusion: Post-tuberculous pulmonary function impairment is frequent phenomenon. After tuberculosis treatment, nearly half of all tuberculosis patients evolve to impaired pulmonary impairment, mainly mixed disorder. Sensitization of patient with symptoms of pulmonary impairment after tuberculosis for an earlier visit to healthcare facilities could reduce the impact of PTB on exercise capacity and health related quality of patients.
Keywords: Pulmonary Impairment, Tuberculosis, PIAT, Exercise Intolerance.
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Corresponding Author
Dr Komal Lohchab
Department of Pulmonary Medicine, S.N. Medical College, Agra UP, India