Title: A Review on the CNS Activity of Pyrazolines
Authors: Swathi V, Shine Sudev, Dhanya K, Anju Jose, Sreelakshmi
DOI: https://dx.doi.org/10.18535/jmscr/v7i11.107
Abstract
The five membered heterocyclic compound pyrazoline is a significant group in heterocyclic chemistry. Many pyrazoline compounds are found possess broad spectrum of biological activities. They are found to possess anti convulsant, neuroprotective, antidepressant, anti inflammatory, anticancer, antimicrobial activities etc. Various pyrazoline derivatives were synthesized and their CNS activities were studied In this review various CNS activities of pyrazolines were discussed. The results shows that pyrazolines and it’s derivatives found to possess CNS activity.
Keywords: Pyrazolines, CNS activity, molecular docking, antidepressant.
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