Abstract
Acute pancreatitis is a rare and serious complication during pregnancy, which can have a high maternal mortality and perinatal mortality. Acute pancreatitis in pregnancy poses diagnostic and therapeutic challenges. The most common cause of acute pancreatitis in pregnancy is gallstones and hypertriglyceridemia. We report a case of acute pancreatitis in a pregnant woman in her third trimester and discuss the analytical and restorative challenges of acute pancreatitis in pregnancy. Even though it is a rare, acute pancreatitis should be suspected in all pregnant patients admitted for non-obstetric abdominal pain. Early diagnosis and good supportive care by a multidisciplinary team are essential to ensure good maternal and fetal outcome.
Keywords: Acute pancreatitis, pregnancy, hypertriglyceridemia, prognosis, treatment.
References
- Vege SS, Yadav D, Chari ST. Pancreatitis. In: GI Epidemiology, 1st ed, Talley NJ, Locke GR, Saito YA (Eds), Blackwell Publishing, Malden, MA 2007.
- Ducarme, F. maire, P. Chatel, D. Luton, P. hammel. “Acute pancreatitis during pregnancy: a review”. Journal of Perinatology 2014; 34:87-94.
- Efstathios P. Papadakis, Maria Sarigianni, Dimitri P. Mikhailidis, Apostolos Mamopoulos, Vasilios Karagiannis. “Acute pancreatitis in pregnancy: an overview. European Journal of obstetrics and Gynecology and Reproductive Biology” 2011; 159:261-266.
- Bahiya Abdullah, Thanikasalam Kathiresan Pillai, Lim HuayCheen, and Ray Joshua Ryan. “Severe acute pancreatitis in pregnancy. Case Reports in Obstetrics and Gynecology” 2015;
- Sarles H. Pancreatitis symposium. Basel SK, Marseille 1963.
- Sarles H. Revised classification of pancreatitis--Marseille 1984. Dig Dis Sci 1985; 30:573.
- Pitchumoni C. S., Yegneswaran B. “Acute pancreatitis in pregnancy”. World Journal of Gastroenterology. 2009; 15(45):5641–5646. doi: 10.3748/wjg.15.5641.
- Ko C. W., Beresford S. A. A., Schulte S. J., Matsumoto A. M., Lee S. P. “Incidence, natural history, and risk factors for biliary sludge and stones during pregnancy”. Hepatology. 2005; 41(2):359–365. doi: 10.1002/hep.20534.
- Eddy J. J., Gideonsen M. D., Song J. Y., Grobman W. A., O’Halloran P. “Pancreatitis in pregnancy”. Obstetrics and Gynecology. 2008; 112(5): 1075–1081. doi: 10.1097/AOG.0b013e318185a032.
- Mindaugas Serpytis, Vytautas Karosas, Rokas Tamosauskas, et al. “Hypertriglyceridemia – induced acute pancreatitis in pregnancy”. JOP J Pancreas (Online) 2012 Nov; 13(6):677-680.
- Thulasidass K., Chowdhury T. A. “Hypertriglyceridemic pancreatitis in pregnancy: case reports and review of the literature”. JRSM Short Reports. 2013; 4(8):1–3. doi: 10.1177/2042533313481211.
- Noel R. A., Braun D. K., Patterson R. E., Bloomgren G. L. “Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study”. Diabetes Care. 2009; 32(5):834–838. doi: 10.2337/dc08-1755.
- Sahu S, Raghuvanshi S, Bahl DV, Sachan P. “Acute Pancreatitis In Pregnancy”. Int J Surg. 2006; 11: Number 2.
- Papadakis E. P., Sarigianni M., Mikhailidis D. P., Mamopoulos A., Karagiannis V. “Acute pancreatitis in pregnancy: an overview”. European Journal of Obstetrics Gynecology and Reproductive Biology. 2011; 159(2):261–266. doi: 10.1016/j.ejogrb.2011.07.037.
- Pandey R., Jacob A., Brooks H. “Acute pancreatitis in pregnancy: review of three cases and anaesthetic management”. International Journal of Obstetric Anesthesia. 2012; 21(4):360–363. doi: 10.1016/j.ijoa.2012.07.004.
- Banks P. A., Bollen T. L., Dervenis C., et al. “Classification of acute pancreatitis”—2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013; 62(1):102–111.
- Tang S.-J., Rodriguez-Frias E., Singh S., et al. “Acute pancreatitis during pregnancy”. Clinical Gastroenterology and Hepatology. 2010; 8(1):85–90. doi: 10.1016/j.cgh.2009.08.035.
- Štimac T., Štimac D.“Acute Pancreatitis During Pregnancy”. 2012.
- Jafri N. S., Mahid S. S., Idstein S. R., Hornung C. A., Galandiuk S. “Antibiotic prophylaxis is not protective in severe acute pancreatitis: a systematic review and meta-analysis”. The American Journal of Surgery. 2009; 197(6):806–813. doi: 10.1016/j.amjsurg.2008.08.016.
- Wilkinson E. J. “Acute pancreatitis in pregnancy: a review of 98 cases and a report of 8 new cases”. Obstetrical and Gynecological Survey. 1973; 28(5):281–303. doi: 10.1097/00006254-197305000-00001.
- Zhang D.-L., Huang Y., Yan L., Phu A., Ran X., Li S.-S. “Thirty-eight cases of acute pancreatitis in pregnancy: a 6-year single center retrospective analysis”. Journal of Huazhong University of Science and Technology [Medical Sciences]2013; 33(3):361–367. doi: 10.1007/s11596-013-1125-8.
- Sun Y., Fan C., Wang S. “Clinical analysis of 16 patients with acute pancreatitis in the third trimester of pregnancy”. International Journal of Clinical and Experimental Pathology. 2013; 6(8):1696–1701.
- Shoaib Gangat A. R., Muhammad A., Saher F., Ameer A., Iqbal Ahmed M. “Frequency of acute pancreatitis in pregnancy and it’s outcome”. Pakistan Journal of Surgery. 2009; 25(2):69–71.
Corresponding Author
Dr Suganya Devi. A
Postal Address- Sri Devi Explosives, Opp. R.C.Plant, Raman Nagar (Post), Mettur Dam- 636 403,
Salem (District), India
DOI: https://dx.doi.org/10.18535/jmscr/v7i9.132
