Abstract
Objective: To study the prevalence of semen abnormalities (Teratozoospermia, Asthenozoospermia and Oligozoospermia) amongst cases indulging in alcohol use and tobacco smoking and chewing.
Material & Method: This study was carried out in Pathology Department, HIMS, Dehradun. Of the 220 cases reported over a period of 12 month, 30 cases each were selected for control group (A) and study groups- Alcohol users (B), Smokers (C), Tobacco chewers (D) and those with all three addiction (E). Standard protocol as per WHO was used to study various semen parameters. Teratozoospermia was studied by two independent observers. Study groups were compared with controls and data was analysed.
Results: Teratozoospermia (T) was the most frequently found variable (n=127/174, 72.8 %). Asthenozoospermia (A) was the second most frequent semen variable (n=113/174, 65.8 %), while oligozoospermia (O) was present in 55.4 % cases (n=97/174). Asthenozoospermia was the most predominant finding in case with gutka addiction (n=21/74), Teratozoospermia was the most predominant finding in case with all three addictions (n=23/79).
Conclusion: Lifestyle factors like cigarette smoking and alcohol intake do produce significant negative impact on semen quality.
Keywords: Asthenozoospermia, Teratozoospermia, Oligozoospermia, Lifestyle factor.
References
- Jurewicz J, Radwan M, Sobala W, Ligocka D, Radwan P, Bochenek M & henke W. Lifestyle and semen quality: role of modifiable risk factors. Systems Biology in Reproductive Medicine, 2014; 60:1, 43-51.
- Gaur DS, Talekar MS, Pathak V. Effect of cigarette smoking on semen quality of infertile men. Singapore Med J. 2007; 48: 119-23
- Bigazzi PE. Immunology of the male reproductive system. New York: Marcel Dekker; 1987.
- Saaranen M, Suonio S, Kauhanen O, Saarikoski S. Cigarette smoking and semen quality in men of reproductive age. Andrologia. 1987; 19:670-6
- Tamer M. Said, Ranga G, Agarwal A. Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation. Fertility and Sterility. 2005;84(3): 649-53.
- Chohan KR, Badawy SZA. Cigarette smoking impairs Sperm bioenergetics. International Braz J Urol. 2010; 36(1): 60-5.
- Gordon GG, Altman K, Southern AL, Rubin E, Leiber CS. The effect of alcohol administration on sex hormone metabolism on normal men. N Engl J Med. 1976;295(15):793-7.
- World health organization. Laboratory manual for examination of human semen and sperm-cervical mucus interaction. 3rd Newyork: Cambridge University Press, 1992.
- Gaur DS, Talekar MS, Pathak V. Alcohol intake and cigarette smoking: Impact of two major lifestyle factors on male fertility. Indian J Pathol Microbiol. 2010; 53:35-40.
- Sansone A, Dato CD, Angelis C, Menafra D, Pozza C, Pivonello R. Smoke, alcohol and drug addiction and male fertility. Reproductive Biology and Endocrinology. 2018; 16:3.
- Albadri CT, Al Ani IM, Hiba HMA. Alcohol consumption and its effect on testicular structure and on sperm count and motility in parent mice and their offspring. The International Journal Malaysia. June 2013, vol 12:1.
- Goverde HJ, Dekker HS, Janessen HJ, Bastiaans BA, Rolland R, Zielhuis GA. Semen quality and frequency of smoking and alcohol consumption- an explorative study. Int J Fertil Menopausal Stud 1995;40:135-8.
- Asare-Anane H, Baninson SB, Ofori EK, Ateko RO, Bawah AT, Amanquah SD, Oppong SY, Gandau BBN, and Ziem JB. Tobacco smoking is associated with decreased semen quality. Reprod Health. 2016; 13: 90
- Kumar R, Gautam G. Tobacco chewing and male infertility. Indian J Urol. 2006;22:161-2.
- Sunanda P, Panda B, Dash C, Ray PK, Padhy RN, Routray P. Prevalence of abnormal spermatozoa in tobacco chewing sub-fertile males. J Hum Reprod Sci. 2014;7:136-42.
Corresponding Author
Manish Kumar Verma
Department of Physiology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
DOI: https://dx.doi.org/10.18535/jmscr/v7i9.121
