Abstract
Background: Laparoscopic technique has almost replaced the open method of cholecystectomy. The anesthesia for laparoscopic cholecystectomy is very challenging because of the effects of pneumoperitoneum on various organ systems mainly the cardiovascular system. In this study we have compared the efficacy of intravenous clonidine as compared to oral clonidine in reducing the hemodynamic effects of pneumoperitoneum.
Materials and Methods: This prospective randomized controlled study was performed in 70 patients posted for elective laparoscopic cholecystectomy in a tertiary care centre. Patients were randomized into two groups, Group 1 patients receiving 3 µg/kg of oral clonidine and Group 2 patients receiving 3 µg/kg of intravenous clonidine. Blood pressure, Heart rate were monitored at appropriate intervals
Results: Patients in both groups had reduced hemodynamic responses to pneumoperitoneum. The incidence of hypotension and bradycardia were more common in the in the iv Clonidine group.
Conclusion: Premedication with oral clonidine is equally efficacious as intravenous clonidine in reducing the hemodynamic stress response to pneumoperitoneum.
Keywords: Laparoscopic cholecystectomy, pneumoperitoneum, clonidine.
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Corresponding Author
Sethunadh R
Assistant Professor, Department of Anaesthesia, Government Medical College, Kottayam, Kerala
DOI: https://dx.doi.org/10.18535/jmscr/v7i9.70
