Title: Evaluation of the Effect of Various Intra Operative Surgical Complications on Central Corneal Endothelial Cell Density and Central Corneal Thickness- A Prospective Study
Authors: Dr Sachin Tammannavar, Dr Ramesh, Janice Reema Lewis, Harshitha, Hemanth Raju M R
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.174
Abstract
Purpose: To evaluate the effect of various intra operative surgical complications on Central Corneal Endothelial Cell Density and Central Corneal Thickness
Methods: A prospective study comprising of 222 patients who underwent small incision cataract surgery, which were divided into three groups.
G1 -Irrigating vectis technique-73 patients
G2-Sandwich technique-75 patients
G3 -Visco expression technique-74 patients.
All patients underwent complete ophthalmic examination and biometry followed by measurement of central corneal thickness, specular microscopy (endothelial images) was performed at baseline (preoperative) and postoperatively at 1week, 2 weeks, 1 month and 3 months.
Results: In our study, out of 222 patients, 180 patients had uneventful and 42 patients had complicated surgeries. In that 42 complicated surgeries,
-11 patients had instrumental trauma (26.2%) which caused 25.2% endothelial cell loss (p value 0.001) and 5% increase in CCT.
-14 patients had Iris prolapse (33.3%) which caused 19.1% cell loss (p value 0.001) and 0.9% increase in CCT
-7 patients had IOL Contact (16.7%) which caused 13.1% cell loss (p value 0.003) and 1.9% increase in CCT
-9 patients had vitreous loss (21.4%) which caused 11.5% cell loss (p value 0.039) and 0.9% increase in CCT and 1 patient had Iris posterior capsular rent (2.4%) which caused 11.3% cell loss and 0.9% increase in CCT at 3 months post operatively.
In all 42 complicated surgeries, average 10.6% cell loss and 5.8% increase in CCT was found.
In all 180 uneventful surgeries, average 9.5% cell loss and 3.48% increase in CCT was found.
Conclusion: Percentage of endothelial cell loss and increase in central corneal thickness was more in complicated surgeries, than uneventful surgeries.
