Abstract
Background: Refractive error are one of the most common ocular disorders. Central corneal thickness (CCT) differs in myopia and hypermetropia, the differences in which can affect the measured Intraocular pressure (IOP).CCT & IOP also undergo changes with advancing age.
Aim: To measure difference in Intra ocular pressure between myopes and hypermetropes. To measure difference in central corneal thickness between myopes and hypermetropes. To note any variation in CCT and IOP that occurs with advancing age.
Materials & Methods: This was a prospective study comprising 104 myopic subjects and 136 hypermetropic subjects above age of 40 who went full ophthalmological examination with emphasis on IOP & CCT.
Results: The intraocular pressure (mmHg) was on the higher side in myopes (15.090, 15.490) whereas in hypermetropes (13.480,13.490). Intraocular pressure varies with age. As age advances there is a fluctuation in the measured IOP with a tendency to decrease, a higher IOP(14.53 mmHg, 14.61mmHg) was seen from ages 40 to 50 as compared to the other age groups. A thicker cornea was seen in hypermetropes (0.542mm, 0.543mm), while myopes (0,532mm,0.537mm) had a thinner cornea. A very weak correlation between IOP and CCT. (r=0.10 in both eyes for hypermetropes, r= -0.17, = -0.14 in myopes). Central corneal thickness was lower (0.523mm, 0.528mm) in advanced ages.
Conclusion: IOP was higher in myopes and hence at risk for glaucoma and IOP reduces as age advances. Thicker corneas are seen in hypermetropes leading to falsely high IOP readings and CCT was seen to reduce with age.
Keywords: Central corneal thickness, Intraocular pressure, Hypermetropia, Myopia,
References
- Raju P, V Ramesh S, Arvind H, George R, Baskaran M, Paul P et al. Prevalence of Refractive Errors in a Rural South Indian Population. Investigative Ophthalmology& Visual Science. 2004;45(12):4268.
- Dandona L, Dandona R, Naduvilath TJ, et al. Refractive errors in an urban population in Southern India: the Andhra Pradesh Eye Disease Study. Invest Ophthalmol Vis Sci. 1999;40:2810–2818.
- Abrams Duke-Elder S. Duke-Elder's practice of refraction. 10th ed. Wobum,MA[u.a.]: Elseveir; 1993.
- Damji K, Muni R, Munger R. Influence of Corneal Variables on Accuracy of Intraocular Pressure Measurement. Journal of Glaucoma. 2003;12(1):69-80.
- David R, Zangwill LM, Tessler Z, Yassur Y. The correlation between intraocular pressure and refractive status. Archives of Ophthalmology. 1985 Dec 1;103(12):1812-5.
- Lekskul M, Aimpun P, Nawanopparatskul B, Bumrungsawat S, Trakulmungkijkarn T, Charoenvanichvisit J et al. The correlations between Central Corneal Thickness and age, gender, intraocular pressure and refractive error of aged 12-60 years old in rural Thai community,Journal of the Medical Association of Thailand 2005, 88 Suppl 3:S175-9
- Chang SW, Tsai IL, Hu FR, Lin LL, Shih YF. The cornea in young myopic adults. Br J Ophthalmol 2001;85:961–70.
- Fam HB, How AC, Baskaran M, Lim KY, Chan YH, Aung T. Central corneal thickness and its relationship to myopia in Chinese adults. Br J Ophthalmol 2006;90:1451–3.
- Cho P, Lam C. Factors affecting the central corneal thicknessof Hong Kong Chinese. Curr Eye Res 1999;18:368–74.
- Olsen T, Ehlers N. The thickness of the human cornea as determined by a specular method. ActaOphthalmol. 1984;62:859–871.
- Swann PG, Yap M, Wong E, Bohl T, Bowen K, Gaffney J. Intraocular pressure measurements and corneal centre thickness in Chinese and Caucasian populations. Proceedings of the Ninth Asian-Pacific Optometric Congress. Hong Kong. 1993:66–69.
- Nomura H, Ando F, Niino N, Shimokata H, Miyake Y. The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness. Ophthalmic and Physiological Optics. 2004 Jan;24(1):41-5.
- Shiose Y. The Aging Effect on Intraocular Pressure in an Apparently Normal Population. Archives of Ophthalmology. 1984;102(6):883-887.
- Harold A. Howard M. Leibowitz James P. Ganley Mohandas M. Kini Theodore Colton Rita S The Framingham Eye Study: I. Outline And Major Prevalence Findings American Journal Of Epidemiology, Volume 106, Issue 1, 1 July 1977, Pages 17–32.
Corresponding Author
Dr Akshay Nayak
Address: 2B Shashi Apartments Model House Street, off KR road, Basavangudi, Bangalore, India-560004