Title: To assess correlation between carotid intima-media thickness and dyslipidemia in patients with stroke: A case control study
Authors: Dr Gautam Chand Jingar, Dr Dinesh Parmar, Dr A.K. Jain, Dr Nishant Kamble, Dr Dinesh Kumar, Dr Vivek Lakhawat
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.43
Abstract
Background: Stroke is a major cause of morbidity and mortality worldwide. An early sign of atherosclerosis is hypertrophy of the arterial wall. Increased intima-media thickness (IMT) is a non-invasive marker of arterial wall alteration, which can easily be assessed in the carotid arteries by high-resolution B-mode ultrasound. Hence it was sought to assess correlation between carotid intima-media thickness and dyslipidemia in patients with stroke.
Material & Methods: The study was conducted at Department of Medicine, in collaboration with Department of Radiology at Dr. S.N.M.C. & M.D.M. hospital, Jodhpur by selecting 70 patients out of which 50 were clinically and CT Scan proved cases of CVA and 20 are age-sex matched healthy control group, from medical outpatients department and indoor patients admitted to hospital. Case group contain patients of varied age group of both male and female sex who were having Stroke attending the general MOPD and emergency department. Control group included the normal healthy person without any evidence of Stroke and comorbid conditions.
Results: Our study suggest that increased carotid intima-media thickness is more associated with infarct patients whereas in hemorrhage patients CIMT is usually normal. Our study showed that cholesterol, Triglyceride, LDL Cholesterol, LDL/HDL Ratio have positive association with CIMT in infarct with p value 0.025, 0.049, 0.013 & 0.003 respectively which is significant. HDL Cholesterol & Chol/HDL Ratio had no positive association with CIMT in infarct with p value 0.333, 0.53 respectively which is not significant.
Conclusion: We concluded that CIMT and LDL/HDL ratio can be used as screening test for all persons who are at higher risk to get stroke such as diabetes, hypertension, obesity, smoker etc.
Keywords: Carotid intima-thickness, Infarct, Hemorrhage, Lipid profile.
