Title: Von Recklinghausen Disease with Vitiligo: A Rare Association
Authors: G.R. Tegta, Saru Thakur, Ajeet Negi, Ghanshyam Verma, Mudita Gupta, Kuldeep Verma
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.32
Abstract
Von Recklinghausen disease, also known as neurofibromatosis 1 is one of the commonest neurocutaneous disorders. It is associated with an increased risk of developing benign and malignant tumors. However, only few case reports are mentioned in literature associating neurofibromatosis with autoimmune disorders, vitiligo being one of them. We report a case of 30 years old female, who presented with cutaneous features of neurofibromatosis 1 and vitiligo. Interestingly, she had multiple neurofibromas, which were characteristically depigmented. Only few case reports have been mentioned in literature associating these two disorders. Whether this exists due to some underlying genetic defect of NF1 gene or mere coincidence, it is yet to be found.
Keywords: neurofibromatosis, vitiligo, coincidence.
