Abstract
Background: Idiopathic granulomatous mastitis (IGM) is an unusual chronic inflammatory disease of the breast with undefined optimal treatment schedule.
Objective: In this study our main goal is to evaluate the application of steroid therapy along with wide local excision in the treatment of IGM.
Method: This retrospectively observational study was carried out Private Hospitals at Dhaka and Patuakhali from march 2016 to march 2017 where 30 GM patients characteristics, symptoms, results of the diagnostic workup, treatment, and outcome evaluated.
Result: during the study,71% patients belonged to 25 to 34 years age range and focal homogeneous enhancing masses with irregular borders found in 5 cases. Also found 98.2% recovered initially after surgical excision with steroid treatment.
Conclusion: we can conclude that for GM excision along with systemic steroid therapy is superior to steroid therapy which provides strict diagnosis as well as much faster healing and less complications. Further study is needed for better outcome.
Keywords: Idiopathic granulomatous mastitis (IGM) chronic, Steroid treatment.
References
- Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J ClinPathol. 1972;58:642–646.
- Erhan Y, Veral A, Kara E, Ozdemir N, Kapkac M, Ozdedeli E, et al. A clinicopathologic study of a rare clinical entity mimicking breast carcinoma: idiopathic granulomatous mastitis. Breast. 2000;9:52–56.
- Asoglu O, Ozmen V, Karanlik H, Tunaci M, Cabioglu N, Igci A, et al. Feasibility of surgical management in patients with granulomatous mastitis. Breast J. 2005;11:108–114.
- Cohen C. Granulomatous mastitis. A review of 5 cases. S Afr Med J. 1977;52:14–16.
- Akcan, Alper, A. BahadırÖz, SerapDogan, HülyaAkgün, MuhammetAkyüz, Engin Ok, Mustafa Gök, and TutkunTalih. "Idiopathic granulomatous mastitis: comparison of wide local excision with or without corticosteroid therapy." Breast Care 9, no. 2 (2014): 111-111.
- Akcan A, Akyildiz H, Deneme MA, Akgun H, Aritas Y: Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg 2006;30:1403–1409.
- Tuncbilek N, Karakas HM, Otken OO: Imaging of granulomatous mastitis: assessment of three cases. Breast 2004;13:510–514.
- Diesing D, Axt-Fliedner R, Hornung D, Weiss JM, Diedrich K, Friedrich M: Granulomatous mastitis. Arch GynecolObstet 2004;269:233–236.
- Lai EC, Chan WC, Ma TK, Tang AP, Poon CS, Leong HT: The role of conservative treatment in idiopathic granulomatous mastitis. Breast J 2005;11:454–456.
- Erhan Y, Veral A, Kara E, Ozdemir N, Kapkac M, Ozdedeli E, Yilmaz R, Koyuncu A, Erhan Y, Ozbal O: A clinicopathologic study of a rare clinical entity mimicking breast carcinoma: idiopathic granulomatous mastitis. Breast 2000;9:52–56
- Asoglu O, Ozmen V, Karanlik H, Tunaci M, Cabioglu N, Igci A, Selcuk UE, Kecer M: Feasibility of surgical management in patients with granulomatous mastitis. Breast J 2005;11:108–114.
- Heer R, Shrimankar J, Griffith CD: Granulomatous mastitis can mimic breast cancer on clinical, radiological or cytological examination: a cautionary tale. Breast 2003;12:283–286.
- Imoto S, Kitaya T, Kodama T, Hasebe T, Mukai K: Idiopathic granulomatous mastitis: case report and review of the literature. Jpn J ClinOncol 1997;27:274–277
- Bani-Hani KE, Yaghan RJ, Matalka II, Shatnawi NJ: Idiopathic granulomatous mastitis: time to avoid unnecessary mastectomies. Breast J 2004;10:318–322.
- Harris SH, Khan MA, Khan R, Haque F, Syed A, Ansari MM: Mammary tuberculosis: analysis of thirty-eight patients. ANZ J Surg 2006;76:234–7.
- Sriram K, Moffatt D, Stapledon R: Tuberculosis infection of the breast mistaken for granulomatous mastitis: a case report. Cases J 2008;1:273
- Tuli R, O’Hara BJ, Hines J, Rosenberg AL: Idiopathic granulomatous mastitis masquerading as carcinoma of the breast: a case report and review of the literature. IntSeminSurgOncol 2007;4:21.
Corresponding Author
Dr Din Mohammad
MBBS, FCPS (Surgery), MRCS (UK), Associate Professor of Surgery, Patuakhali Medical College, Patuakhali, Bangladesh