Abstract
Microbes are the sources of various enzymes which are commercially important. Some enzymes, particularly L-glutaminase and L-asparaginase are medically important as they can be used for the treatment of leukemia. Many bacteria reported to produce L-glutaminase which can be used as an anticancer agent. L-glutaminase is used in the preparation of baked foods to increase the flavor of the foods. In the present paper five L-glutaminase producing bacteria were isolated from garden, market area and agricultural soils using minimal L-glutamine medium supplemented with phenol red indicator. Based on microscopic examination and biochemical characterization the bacteria were identified as Pseudomonas, Serratia, Proteus, Staphylococus and Bacillus species. These bacteria can be improved and exploited for the commercial production of L-glutaminase.
Keywords: L-glutaminase, leukemia, anticancer, L-glutaminase producing bacteria.
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Corresponding Author
Dr Praveen Reddy.P
Department of Microbiology, Vivekananda Degree and PG College, Karimnagar-505001, Telangana, India