Title: A case of Mixed Connective Tissue Disease with Right Heart Failure
Authors: Dr Venkatesh R, Dr Nagarajan K, Dr Anand P
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.09
Abstract
Background: Sharp and colleagues in 1972 was first described the Mixed connectivetissue disease (MCTD).They described MCTD in a group of people havingwith overlapping clinical features of scleroderma, myositis and systemic lupus erythematosus (SLE) with the presence of a specific antibody against U1-ribonucleoprotein (RNP).1 Sharp's syndrome is the other name for MCTD.2 It is more common in females than males. Estimations of the female to male ratio varies from approximately 3:1 to 16:1.3,4It is typically occuring between 15-25 years oldbut it can occur at any age but in our country has rarely been reported but here by reported rare presentation of MCTD occurs in 65 years old female.
Keywords: Mixed connective tissue disease; Pulmonary hypertension; Extractable nuclear antigen.
Background: Sharp and colleagues in 1972 was first described the Mixed connectivetissue disease (MCTD).They described MCTD in a group of people havingwith overlapping clinical features of scleroderma, myositis and systemic lupus erythematosus (SLE) with the presence of a specific antibody against U1-ribonucleoprotein (RNP).1 Sharp's syndrome is the other name for MCTD.2 It is more common in females than males. Estimations of the female to male ratio varies from approximately 3:1 to 16:1.3,4It is typically occuring between 15-25 years oldbut it can occur at any age but in our country has rarely been reported but here by reported rare presentation of MCTD occurs in 65 years old female.
Keywords: Mixed connective tissue disease; Pulmonary hypertension; Extractable nuclear antigen.
