Abstract
Introduction: Breast lesions are very common in India. FNAC is a reliable method for the initial evaluation and diagnosis of palpable masses of the breast.
Objectives: 1. To study the cytological features of palpable breast lumps.
- To correlate the cytological and histological features.
Material and Methods: Present study was carried out on 84 patients who presented with palpable breast lumps. Cytological evaluation was done along with histological correlation. Sensitivity, specificity and diagnostic accuracy of FNAC were calculated.
Results: Out of the 84 cases, 62 were benign (73.8%) while 22 were malignant (26.1%). On histological correlation, out of the 62 benign cases cytologically, 60 were benign histologically also while 2 turned out to be malignant on histology. On the other hand, out of the 22 malignant cases on cytology, 21 cases were malignant on histology as well while 1 case turned out to be benign.
Conclusion: FNAC has a very high sensitivity, specificity and diagnostic accuracy along with low cost and few side effects. Thus, it is quite useful for the diagnosis of breast lumps and can be an important tool in screening of breast cancer patients.
Keywords: Cytological evaluation, breast lumps.
References
- David J Dabbs. Prognostic information from the fine needle aspiration biopsy of breast Am J of Clinical Pathol 2000;113(1):76-83.
- Rosa, A Mohammadi, and S. Masood, “The value of fine needle aspiration biopsy in the diagnosis and prognostic assessment of palpable breast lesions, “Diagnostic Cytopathology,2012, vol.40, no.1, pp.26-34
- Rekha TS, Nandini NM. Validity of different Cytological Grading Systems of Breast Carcinoma – a hospital based study in South India. Asia Pacific Journal of Cancer Prevention. 2011;12:3013-5
- Lindholm K. Breast. In: Manual and atlas of fine needle aspiration cytology, Orell SR, Sterrett GF, Walters MNI, Whitaker D, 4th ed. India: Churchill Livingstone; 2005. pp.165- 226
- Kumar R. A clinicopathologic study of breat lumps in Bhairahwa, Nepal. Asian Pac J Cancer Prev. 2010;11:855–8
- Eleuterio J Jr, Aragao A, Cavalcante DI. FNA of breast lesions: Surepath liquid based technique versus conventional smears. Acta Cytol 2015;59:253-7.
- Das AK, Kapila K, Dinda AK, Verma K. Comparative evaluation of grading of breast carcinomas in fine needle aspirates by two methods. Indian J Med Res 2003;118:247-50.
- Meena SP, Hemrajani DK, Joshi N. A comparative and evaluative study of cytological and histological grading system profile in malignant neoplasm of breast – an important prognostic factor. Indian J Pathol Microbiol 2006;49:199- 202
- Ferguson CM, Powell RW. Breast masses in women. Arch Surg. 1989;124:1338.
- Chandanwale SS, Gupta K, Dharwadkar AA, Pal S, Buch AC, Mishra N. Pattern of palpable breast lesions on fi ne needle aspiration: A retrospective analysis of 902 cases. J Midlife Health 2014;5:186-91.
- Kujur P. Fine-Needle Aspiration Cytology of the Palpable Breast lump of 106 Cases and Correlation with Histologic Diagnosis:A Prospective Analysis. Int J Sci Stud 2015;3(9):111-115.
- Sankaye SB, Dongre SD. Cytological study of palpable breast lumps presenting in an Indian rural setup. Indian J Med Paediatr Oncol 2014;35:159-64.
- Coen P, Kulin H, Ballantine T, Zaino R, Frauenhoffer E, Boal D, et al. An aromatase-producing sex-cord tumour resulting in prepubertal gynaecomastia. N Engl J Med.1991;324:317–22.
- Likhar KS, Fatima A, Hazari RA, Gupta SG, Shukla U. Diagnostic role of FNAC in breast IJRRMS 2013;3:12-4.
- Handa U, Kumar A, Kundu R, Dalal U, Mohan H. Evaluation of grading and hormone receptor immunostaining on fi ne needle aspirates in carcinoma breast. J Cytol 2015;32:1-5.
- Hammond S, Keyhan I, Rofagha S. Statistical analysis of fine needle aspiration cytology of Breast: A review of 678 cases plus 4265 cases from literature. Acta Cytologica 1987;31:276-280.
- Bhagat R, Bal MS, Bodal VK, Suri AK, Jindal K. Cytological study of palpable breast lumps with their histological correlation. Int J Med and Dent Sci 2013;2(2): 128-136.
- Rao DN, Ganesh B. Estimate of cancer incidence in India in 1991. Indian J Cancer. 1998;35:10-18.
Corresponding Author
Dr Lalit Mohan Patel
Senior Resident, Department of Radiotherapy, NSCB Medical College, Jabalpur, India
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.02
