Abstract
Introduction: Diabetes is the major concern of today’s world and its chronic complications have become a serious public health issue. Diabetes getting detected in the pre diabetic phase will be of great help in decreasing the morbidity and mortality arising due to the complications
Methodology: We studied a total sample of 528 patients coming to the medicine outpatient department, age group from 18-40 years, who underwent a series of investigations of fasting, post prandial and HbA1c tests and were grouped according to the newer definition of American Diabetic Association in the pre diabetic groups. The modifiable risk factors were compared amongst them.
Results: The data was analysed and compared in relation with age, sex, type of family, maritalstatus, occupation, education, Body mass index, waist hip ratio, alcoholic status, smoking and diastolic blood pressure and systolic blood pressure and physical activity to the prediabetic status.
Conclusion : An effort to establish the association of modifiable risk factors with prediabetic condition was made in order to effectively target and tackle these factors so as to successfully manage, predict and prevent or slow the progression of prediabetic condition from converting into overt diabetes.
Keywords: Prediabetes, modifiable risk factors.
References
- American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. 2010; Suppl 1, S62-S67.
- Cheng D. Prevalence, predisposition and prevention of type II diabetes. Nutr Metab (Lond) 2005; 2: 29.
- World Health Organization. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: report of a WHO/IDF consultation. Geneva, Switzerland, World Health Organization. 2006.
- Tabak AG, Herder C, Rathmann W, Brunner EJ &Kivimaki M. Prediabetes: a highrisk state for diabetes development. Lancet 2012; 379: 2279–2290.
- Suzuki, H, Oda,E, Aizawa,Y. Comparison between Prediabetes Defined by Hemoglobin HbA1c (HBA1C) 5.7–6.4% and that Defined by Impaired Fasting Glucose (IFG) in a Japanese Population. Diabetes & Metabolism 2011; 38: 1055–1059.
- Borg R, Vistisen D, Witte DR &Borch-Johnsen K. Comparing risk profiles of individuals diagnosed with diabetes by OGTT and HbHbA1c The Danish Inter99 study. Diabet Med 2010; 27: 906–910.
- Hedblad B, Nilsson P, Engstrom G, Berglund G &Janzon L. Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death. Diabet Med 2002;19: 470–475.
- Ausk KJ, Boyko EJ &Ioannou GN. Insulin resistance predicts mortality in nondiabetic individuals in the U.S. Diabetes Care 2010; 33: 1179–1185.
- Lorenzo C, Wagenknecht LE, Hanley AJ, Rewers MJ, Karter AJ & Haffner SM. HBA1C between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care 2010; 33: 2104–2109.
- Ford ES, Zhao G & Li C. Pre-diabetes and the risk for cardiovascular disease: a systematic review of the evidence. J Am CollCardiol 2010; 55: 1310–1317.
- Muthunarayanan L, Ramraj B, Russel JK. Prevalence of prediabetes and its associated risk factors among rural adults in Tamil Nadu. Arch Med Health Sci 2015;3:178-84.
- Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, Unnikrishnan R, et al. Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: Phase I results of the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study. Diabetologia 2011;54:3022-7.
- Snehalatha C, Ramachandran A, Satyavani K, Sivasankari S, Vijay V. Clustering of cardiovascular risk factors in impaired fasting glucose and impaired glucose tolerance. Int J Diabetes DevCtries 2003;23:58-60
- Lakka TA, Laukkanen JA, Rauramaa R, Salonen R, Lakka HM, Kaplan GA &Salonen JT. Cardiorespiratory fitness and the progression of carotid atherosclerosis in middle-aged men. Ann Intern Med 2001; 134: 12–20.
- Akter S, Rahman MM, Abe SK, Sultana P. Prevalence of diabetes and prediabetes and their risk factors among Bangladeshi adults: A nationwide survey. Bull World Health Organ 2014;92:204-213
- Al-Shafaee MA, Bhargava K, Al-Farsi YM, Mcilvenny S, Al-Mandhari A, Al-Adawi S, et al. Prevalence of pre-diabetes and associated risk factors in a n adult Omani population. Int J Diabetes DevCtries 2011;31:166-74.
Corresponding Author
Dr Rishi Patel
Professor, Bharati Hospital and Research Centre, Dhankawadi, Pune 411043, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone number - 9960512343