Abstract
Background: One of the major complication of diabetes mellitus (DM) is cardiovascular disease, which is the main cause of death in patients of north Indians. Hyperglycemia leads to the risk of inflammation as well as vascular damage through various mechanisms. This study was being conducted to evaluate the role C-Reactive Protein (CRP) as as inflammatory marker in type 2 DM with IHD and type 2 DM without IHD patients.
Methodology: A comparative study was conducted. The present study were assessed the fasting blood glucose and C-reactive protein levels in two groups. Group A comprised of 50 diabetic patients with Ischemic heart disease (IHD) , Group B consist of 50 diabetic patient without IHD. All the patients were selected from Govt. Medical College, Amritsar.
Result: The mean of CRP and Fasting blood glucose (FBS) were significantly (P<0.05) high in type 2 diabetic patient with IHD as compared to type 2 diabetic patient without IHD .
Conclusion: It is concluded that there is significance association between the level of serum CRP and FBS. Moreover, positive correlation between CRP and FBS has been shown that inflammatory marker is the main indicator of insulin resistance which is observed in type 2 DM without IHD patients and with IHD patients. CRP can be used as a marker for diagnosis of early stages of the risk of IHD in type2 diabetic patients.
Keywords: C-Reactive Protein, Diabetes Mellitus, Ischemic heart disease, Fasting blood sugar.
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Corresponding Author
Dr Tejinder Singh
Senior Resident, Department of Biochemistry, GMC Amritsar, India
DOI: https://dx.doi.org/10.18535/jmscr/v7i4.156
