Abstract
Introduction
Otitis media (OM), an inflammation of the middle ear cleft, is a common problem worldwide. Globally, about 65–330 million people suffer from ear infection and 60 % of them had significant hearing impairment.1It is a prevalent problem for both children and adults especially in developing countries. Due to the low socio-economic status, overcrowding, poor hygiene, inadequate health care, and recurrent upper respiratory tract infection, the burden is high in low and middle income countries.2 Clinically, it is classified as acute, sub-acute and chronic depending on duration. Acute otitis media incidence rate is 10.85 % while chronic suppurative otitis media incidence rate is 4.76 %.3
Infection can be spread from middle-ear to vital structures such as mastoid, facial nerve, labyrinth, lateral sinus, meninges and brain leading to mastoid abscess, facial nerve paralysis, deafness, lateral sinus thrombosis, meningitis and intracranial abscess.4 Moreover normal flora of the skin such as Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumonia and Escherichia coli that can easily enter through perforated ear have been reported as the main agents of otitis media.5
Empiric treatment of ear infection is not always appropriate since drug susceptibility patterns change overtime and empiric antibiotic therapy may not be effective at times and could contribute to development of antimicrobial resistance in the long run.6 Early, prompt and effective treatment of ear infection will significantly reduce both short and long term complications. Hence our study aims at determining the bacterial profile and antimicrobial susceptibility pattern of ear infections among patients in a tertiary care hospital in India.
References
- Woodfield G and DugdaleA. Evidence behind the WHO guidelines: hospital care for children: What is the most effective antibiotic regime for chronicsuppurative otitis media in children. J Tropical Pediatric 2008; 54(3):151–156.
- Kumar H, Seth S. Bacterial and fungal study of 100 cases of chronic suppurative otitis media. J ClinDiagn Res 2011; 5:1224–1227.
- Panchal PD, Patel BV. Evaluation of bacteriological profile and antibiotic susceptibility pattern of patients with otorrhea in a tertiary care teaching hospital. Int J Res Med Sci 2015; 3:3167-70.
- Ulug M and Oksay B. Bacterial isolates and antibiotic susceptibility patterns of ear discharge from patients with chronic suppurative otitis media and review of the literature. June 2014 Sylwan 158(6):1-25.
- Abera B and Kibret M. Bacteriology and antimicrobial susceptibility of otitis media at dessie regional health research laboratory, Ethiopia. Ethiopian J Health Develop 2011; 25(2):161–167.
- Grevers G. Challenges in reducing the burden of otitis media disease: an ENT perspective on improving management and prospects for prevention. Int J Pediatr Otorhinolaryngol. 2010; 74(6):572–7.
- Mackie, McCartney. Practical medical microbiology. In: Mackie, McCartney, eds. 14th ed.US: Kundli Press, Elsevier Publishers; 2012.
- Akter S, Shamsuzzaman SM, Nehar N, Siddiqui I, JahanF,Islam S. Bacterial isolates and drug susceptibility patterns of ear discharge from patients with ear infection at ShaheedMonsur Ali Medical College. Bangladesh J Med Microbiol 2015; 9 (2): 20-23.
- Wasihun AG and Zemene Y. Bacterial profile and antimicrobial susceptibility patterns of otitis media in AyderTeaching and Referral Hospital, Mekelle University, Northern Ethiopia. SpringerPlus 2015; 4:701.
- Agrawal A, Kumar D, Goyal A, Goyal S, Singh N, Khandelwal G. Microbiological profile and their antimicrobial sensitivity pattern in patients of otitis media with ear discharge. Indian J Otol 2013; 19:5-8.
- Madana J, Yolmo D, Kalaiarasi R, Gopalakrishnan S, Sujata S. Microbiological profile with antibiotic sensitivity pattern of cholesteatomatous chronicsuppurative otitis media among children. Int J PediatrOtorhinolaryngol 2011;75:1104‑
- Tahir M, Jawaid A, Abdullah A, Najam MA. Bacterial culture and sensitivity in active chronic otitis media: 500 cases in combined military hospital Rawalpindi. Pak J Otolaryngol 2012;28:56‑
- Gorems K,Beyene G,Berhane M, Mekonnen Z. Antimicrobial susceptibility patterns of bacteria isolated from patients with eardischarge in Jimma Town, Southwest, Ethiopia. BMC Ear, Nose and Throat Disorders 2018; 18:17.
Corresponding Author
Dr Shafiq A
Associate Professor, Department of Surgery, Government Medical College, Srinagar, J&K, India