Abstract
The present study cisatracurium vs rocuronium for endotracheal intubation in adult patients was undertaken to compare the onset of action, intubating conditions, recovery time from neuromuscular blockade, hemodynamic effects of cisatracrium 0.15 mg/kg and rocuronium 0.6mg/kg in 100 adult patients between 20-60 years of age, with ASA physical status I and II of either sex posted for elective surgical procedures after induction with intravenous propofol 2mg/kg and followed by fentanyl 2mcg/kg iv injection. In our study we found that onset of action was quicker and intubating conditions are better and faster with rocuronium (92.02±12.33) compared to cisatracrium(188.45±33.42). There was no statistically significant changes in hemodynamic parameters with both drugs. Intubating conditions were assessed by modified grading given by Cooper et al. It was excellent in 72%, good in 22% and fair in 2% of patients in cisatracrium group, and it was excellent in 78%, good in 14% and fair in 8% of patients in rocuronium group. In all patient the recovery time at TOF>0.9 was between 30–110min. Mean recovery time was 59.33±15.56 and 53±10.23 min in cisatracrium and rocuronium groups respectively. It can be concluded that rocuronium has a rapid onset, time to excellent intubating conditions was significantly faster but both drugs were producing excellent to good intubating conditions with minimal hemodynamic changes and no adverse effects in adult patients of age 20-60 years posted for elective surgery.
Keywords: cisatracurium , rocuronium , endotracheal intubation, on set time, recovery time
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Corresponding Author
Dr. Kiran Kumar. Suggala
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DOI: https://dx.doi.org/10.18535/jmscr/v7i3.193
