Abstract

Carotid Intimal Thickness (CIT) is an early prognostic assessment of carotid atherosclerotic vascular infections and their co-morbidities if there should arise an occurrence of subclinical hypothyroidism and clear hypothyroidism. Subclinical Hypothyroidism (SCH) characterized as biochemical affirmation of thyroid hormone inadequacy in patients who have few or no clear clinical highlights of hypothyroidism.  The occurrence of hostile to TPO antibodies are most delicate test for identifying immune system thyroid malady like Hashimoto's sickness. The cardiovascular points of interest of levothyroxine substitution are not sketchy in obvious hypothyroidism but rather no assent has been accomplished up to this point about the unfriendly cardiovascular issue results of subclinical hypothyroidism and its treatment.  So we compare the carotid intimal thickness (CIT) in subclinical and overt hypothyroidism and their relationship with associated co-morbidities and also we evaluate   subclinical hypothyroidism (SCH) relation with carotid atherosclerotic diseases as well as lipid profile derangement in a tertiary care hospital of Institute of Medical Science and SUM Hospital. The result we obtained conclude that the decrease in Carotid Intimal Thickness (CIT) after taking Levothyroxin treatment in the patients with SCH.  This data recommend early diagnosis of such patients and preventing them from further risks which can be done by early initiation of thyroid hormone replacement in such patients and their proper follow-up.

Keywords: Carotid Intimal Thickness, SCH, Levothyroxin, TPO.