Abstract
Background: Stroke is an acute neurological injury which occurs due to vascular pathology with many modifiable risk factors, dyslipidemia being one of them. In this study lipid profile was studied in non-diabetic patients with stroke, because diabetes itself is associated with hyperlipidemia.
Materials and Methods: The study was conducted on 60 non-diabetic stroke patients and 60 age and sex matched controls who did not have stroke, after obtaining consent.
Results: The study shows the effect of Total Cholesterol, LDL and HDL on stroke.
Conclusion: This study showed significant association of total cholesterol, LDL cholesterol in non-diabetics with stroke. High levels of total cholesterol, LDL were associated with a higher level of stroke. Low levels of HDL were not associated with a higher risk of stroke.
Keywords: dyslipidemia, stroke, cholesterol, cerebrovascular accident, diabetes mellitus.
References
- Harrisons principles of medicine 18th edition.
- Agarwal J.K.Somani. P,N,Nariyar B.C.A Study of risk factors in non-embolic cerebrovascular disease. Neuro India vol 24,3p;125-133;1976.
- The SPARCL investigations (2003) design and baseline characteristics of the stroke prevention by aggressive reduction in cholesterol study. Cerebrovas dis16;389-395.
- Iso H, Jacobs DT, Wentworth D, Neaton JD, Cohen J.D, & for the MRFIT Research group.1989 serum cholesterol levels and six –year mortality from stroke in 350977 men screened for multiple risk factor trial N Engl J Med 320;904-910.
- Kleinman Y et al.serum lipids in acute ischemic stroke .stroke 1997;28;1467.
- Alok Mohankar, Ravindrakumar Garg et al.serum lipids and stroke. Neurology India 1993.
- Hatchinski V Graffagnino C, Beaudry, Bernier G, Buck, Donner A, Spence D,Doid G& WolfeBMF1996.Lipids and stroke a paradox resolved, Arch Neuro53;303-308.
- BenfanteR,Yano k, Hwang L-j et al.elevated serum cholesterol is a risk factor for both coronary heart disease and thromboembolic stroke in Hawaiian Japanese men.stroke1994;25;814.
Corresponding Author
Mythili Seetharaman
Assistant Professor, Rajiv Gandhi Government General Hospital, Chennai – 600003, India
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