Abstract
Recurrent pregnancy loss affects between 1 in 300 couple aspiring for a baby. Potential causes remains unexplained in even up to half of the cases. The objective of the study is to determine if the free T4 & TSH level, USG of pelvic organs, Anti phopholipid antibody, thrombophilia, VDRL, TORCH, other infections, Rh incompatibility, diabetes, deficiency of coagulation inhibitors can be implicated in the increased incidence of fetal loss.
Keywords: Recurrent pregnancy loss, Anti phopholipid antibody.
References
- Edmonds DK, Lindsay KI, Miller JF. Early embryonic mortality in women. Fertil Steril 1982;38:447–453.
- Wilcox AJ, Weinberg CR, O'Connor JF, et al. Incidence of early loss of pregnancy. N Engl J Med 1988;319:189–194.
- Hatasaka HH. Recurrent miscarriage: Epidemiologic factors, definitions and incidence. Clin Obstet Gynecol 1994; 37:625-34.
- Wang J, Trudinger BJ, Duarte N, Wilcken DE, LiWang X. Elevated circulating homocysteine levels in placental vascular disease and associated pre-eclampsia. Br J Obstet Gynaecol 2000;107:935-8.
- Rai R, Regan L. Antiphospholipid syndrome and pregnancy loss. Hosp Med 1998;59:637-9.
- Backos M, Rai R, Baxter N, Chilcott IT, Cohen H, Regan L. Pregnancy complications in women with recurrent miscarriages associated with antiphospholipid antibodies treated with low dose aspirin and heparin. Br J Obstet Gynaecol 1999; 106:102-7.
- Kupferminc MJ, Eldor A, Steinman N, Many A, Bar-Am A, Jaffa A, et al. Increased frequency of genetic thrombo-philia in women with complications of pregnancy. N Engl J Med 1999;340:9-13.
- Alberman E. The epidemiology of repeated abortion. In: Beard RW, Sharp F, eds. Early pregnancy loss: mechanisms and treatment. New York, NY: Springer-Verlag, 1988:9–17.
- Greer IA. Thrombophilia: implications for pregnancy outcome. Thromb Res 2003;109:73–81.
- Lindqvist PG, Svensson PJ, Dahlback B, et al. Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss a possible evolutionary selection mechanism. Thromb Haemost 1998;79:69–73.
Corresponding Author
Dr Subhankar Kumar
Mob: 9830525033, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.