Abstract
Background: Congenital heart disease (CHD) refers to various abnormalities with the structure and functions due to anomalous development of the heart before birth. Usually classified into two types: acyanotic and cyanotic, CHD is the most common type of all birth defects and is responsible for more deaths in the first year of life than any other birth defects.
Objectives: To determine the prevalence and clinical profile in a tertiary medical centre.
Materials and Methods: The study was conducted in the department of Pediatrics, RIMS, Imphal, during a period of two years from August 2011 to July 2013 in which all admitted cases of CHD (0-12 years), were evaluated with detailed history, clinical examinations and routine investigations including chest X-ray (CXR), electrocardiogram (ECG) and confirmed by echocardiography.
Results: 83 children (1.76%) were diagnosed with CHD during the study period of 2 years. Majority of cases (51.8%) were observed in the 1-12 months age group followed by 26.5% in 0-1 month, 18.1% in 1-5 years and 3.6% in 5-12 years age group respectively. Acyanotic congenital heart disease (ACHD) was the commonest type accounting for 86.8% of all CHDs out of ventricular septal defect (VSD) constituted 38.6% of the total CHDs. Among the cyanotic congenital heart disease (CCHD), Tetralogy of Fallot (TOF) was the commonest type constituting 10.8% of all CHDs. The most predominat symptom was breathing difficulty (85.5%) followed by fever (62.7%), cough (60.2%), recurrent chest infection (57.8%), excessive cry (56.6%), reduced feeding (48.2%), increased sweating during feeds (44.6%), failure to thrive (26.5%) and blue lips (13.2%).There were 3(3.6%) mortalities in infants with complex CHDs.
Conclusion: Early diagnosis of CHD will significantly contribute in reducing morbidity and mortality by prioritizing appropriate management.
Keywords: Congenital heart disease, clinical profile, ventricular septal defect, breathlessness.
References
- Bernstein D. Congenital heart disease. Kleigman RM, Bonita, Staton, Geme JS, Schor N, Behrman RE editors. Nelson Textbook of Pediatrics, 19th Edition, International: Elsevier, 2011, 1549.
- Moller JH, Taubert KA, Allen HD. Cardiovascular health and disease in children: Current status. A special writing group from task force on children and youth, American Heart Association. Circulation 1994;89(2):923-30.
- Frommelt MA, Frommelt PC. Advances in echocardiographic diagnostic modalities for the pediatrician. Pediatric Clinics of North America, Philadelphia: Saunders 1999; 46(2):427-39.
- Gupta I, Gupta ML, Parihar A, Gupta CD. Epidemiology of rheumatic and congenital heart disease in school children. J Indian Medical Assoc 1992; 90: 57-59.
- Vashishtha VM, Kalra A, Kalra K, Jain VK. Prevalence of congenital heart disease in school children. Indian Pediatr 1993; 30: 1337-1340.
- Saxena A. Congenital heart disease in India: A status report. Indian J Pediatr 2005;72(7):595-8.
- Kula S, Cevik A, Olgunturk FR, Tunaoglu FS, Oguz AD, Ilhan MN. Distribution of congenital heart disease in Turkey. Turk J Med Sci 2011;41(5):889-93.
- Ibadin MO, Sadoh WE, Osarogiagbon W. Congenital heart diseases at the university of teaching hospital. Niger J Pediatr 2005;32(2):29-32.
- Alabdulgader AAA. Congenital heart disease in 740 subjects: epidemiological aspects. Annals of Tropical Paediatrics: International Child Health 2001;21(2):111-8.
- Marelli AJ, Mackie AS, Ionescu-Ittu R, rahme E, Pilote L. Congenital heart disease in the general population. Changing prevalence and age distribution. Circulation 2007;115:163-72.
- Mughal AR, Sadiq M, Hyder SN, Qureshi AU, Shah SSA, Khan MA et al. Socioeconomic status and impact of treatment on families of children with congenital heart disease. J Coll Physicians Surg Pak 2011;21(7):398-402.
- Sharmin LS, Haque MA, Bari MA, Ali MA. Pattern and clinical profile of congenital heart disease in a teaching hospital. J Teach Assoc 2008;21(2):58-62.
- Tank S, Malik S, Joshi S. Epidemiology of CHD among hospitalized patients. Bombay Heart Journal. 2004; 46(2):144-150.
- Gupte S, Saini G. Congenital heart disease: Clinico echocardiographic profile in children. Asian Journal of Pediatric Practice. 2004; 8(2):30-34.
- Jain KK, Sagar A, Beri S. Heart disease in children. Indian J Pediatr 1971;38:441-48.
- Kasturi L, Kulkarni AV, Amin A, Mahashankar VA. Congenital heart disease: clinical spectrum. Indian Pediatr 1999;36:953.
- Shah GS, Singh MK, Pandey TR, Kalakheti BK, Bhandari GP. Incidence of congenital heart disease in tertiary care hospital. Kathmandu Univ Med J. 2008 Jan-Mar;6(1):33-6.
- Smitha R, Karat SC, Narayanappa D, Krishnamurthy B, Prasanth SN, Ramchandra NB. Prevalence of congenital heart disease in Mysore. Indian J Hum Genet 2006;12(1):11-16.
- Tandon R, Edwards JE. Cardiac Malformations Associated with Down's Syndrome Circulation, Volume XLVII, June 1973; 1349-55.
- Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Revs. 2010;4:CD003481.
- Kumari NR, Raju IB, Patnaik AN, Barik R, Singh A, Pushpanjali A, et al. J Cardiovasc Dis Res 2013;4(1):11-4.
- Miranda JJ, Gilman RH, Smeeth L. Differences in cardiovascular risk factors in rural, urban and rural-to-urban migrants in Peru. Heart 2011;97(10):787-96.
- Kumar N,Sekhar C, kumar P, Kundu AS. Kuppuswamy’s socioeconomic status scale-updating for 2007. Indian j Pedatr 2007;74:131-2.
Corresponding Author
Dr Ch. Shyamsunder
Associate Professor, Department of Pediatrics, RIMS, Imphal, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.182
