Abstract
Objective: The aim of the present study was to determine the incidence of salmonella species and their emerging trends of drug resistance.
Materials and Methods: A total of 96 patients of different age groups and different sex were presenting with complains of high grade fever from 4 to 6 days of duration, severe headache and abdominal pain in medical OPD, were included in the study. After detailed history specially drug history and clinical examination, they were provisionally diagnosed as a typhoid fever. All the suspected typhoid fever patient’s were send to the laboratory for blood culture. Samples were collected in fully aseptic manner. Isolation, Identification and Drug sensitivity pattern of the causative organism were performed according to CLSI guidelines.
Results: Out of 96 patients, 52 (54.17%) patients were comes in 5-20 years of age, which was the commonest and with male preponderance (61.54%). Female to male ratio was 1:1.52. In the present study a total of 72 (75%) isolates obtained from blood culture, they were highly sensitive to chloramphenical (86.12%), Ampicillin (86.11%), and cotrimoxazole (86%). Highest sensitivity was seen for cephalosporins, followed by Quinolones, 6.95% of the strains to be sensitive to all the drugs and 15.28% were multidrug resistance(MDR).
Conclusion: Study indicates reemergence of chloramphenicol susceptible salmonella species.
Keywords: Salmonella, Drug resistance, Typhoid fever, Reemergence, Susceptible.
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Corresponding Author
Dr Satyendu Sagar
Assistant Professor, Department of Microbiology, Nalanda Medical College, Patna, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.59
