Abstract
Introduction: Myasthenia gravis (MG) is an autoimmune disorder that affects the neuromuscular junction (NMJ) at the postsynaptic level. Ocular MG (OMG) is a subtype of MG where the weakness is clinically isolated to the EOMs, levator palpebrae and orbicularis oculi. There is not enough data on the clinico epidemiologic profile of OMG in the Indian population.
Methods: During a period of one year(September 2007 to August 2008),out of 40 consecutive patients of MG 16 patients with a diagnosis of ocular MG presenting to the Neuromuscular clinic, Department of Neurology, at tertiary care referral were recruited for the study. All patients were followed up regularly for a minimum period of 3 years.
Objectives: To describe the clinicoepidemiologic profile and outcome of OMG.
Conclusion: Asymmetric ptosis and diplopia are the commonest manifestations in ocular myasthenia. Steroid is mostly needed in OMG.
Keywords: OMG, Antibodies, diagnosis, Thymoma, immunomodulation.
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Corresponding Author
Dr Thomas Iype
Professor, Professor, Dept. of Neurology, Govt. Medical College, Thiruvananthapuram, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.53
