Abstract
Papillary thyroid carcinoma is the most common cancer in thyroid malignancy. Warthin like variant is unusually rare variant of papillary thyroid carcinoma. We report a case of 35 year old female presented with swelling infront of neck for 6 months, with no pressure symptoms, patient is euthyroid. USG revealed suspicious nodules in isthmus FNAC was done and a diagnosis of papillary carcinoma thyroid was given, patient underwent thyroidectomy, HPR revealed Warthin like variant of papillary carcinoma thyroid and itis extending into perithyroidal fatty tissue and skeletal muscle with lymph node metastasis. Here we document cytomorphology and histopathology of this uncommon variant reported in our institution.
Keywords: Warthin like variant of papillary carcinoma, FNAC.
References
- Apel RL, Asa SL, LiVolsi VA. Papillary Hu¨ rthle cell carcinoma with lymphocytic stroma: ‘‘Warthin’s-like tumor’’ of the thyroid. Am J Surg Pathol. 1995;19:810.
- Eun Young Kim, Kwan Ho Lee,Young Lai Park, chan Heun Park, Dong Hyun Kim, Seoun Wan Chae,Ji Sup Yun . Warthin like papillary Thyroid carcinoma accompanying classical papillary carcinoma. Int J clin Exp Pathol 2017;10(6):7223-7231.
- Zubair W. Baloch, MD, PhD; Virginia A. Li Volsi, MD. Warthin-like Papillary Carcinoma of the Thyroid. Arch Pathol Lab Med—Vol 124, August 2000:1192-1195.
- Rosai J, Carcangiu ML, DeLellis RA. Tumors of the Thyroid Gland. Washington, DC: Armed Forces Institute of Pathology; 1992. Atlas of Tumor Pathology; 3rd series, fascicle 5.
- LiVolsi VA. Surgical Pathology of the Thyroid. Philadelphia, Pa: WB Saunders; 1990.
- Sun Hee Chang, Chang Sig Choi , Yoon Suk Kim. Warthin-like Tumor Variant of Papillary Thyroid Carcinoma, A Case Report. The Korean Journal of Pathology 2004; 38: 200-3
- Amico P, Lanzafame S, Li Destri G, Greco P, Caltabiano R, Vecchio GM and Magro G. Warthin tumor-like papillary thyroid carcinoma with a minor dedifferentiated component: report of a case with clinicopathologic considerations. Case Rep Med 2010; 2010: 495281.
- Panayiotides IG, Foukas PG, Meristoudis C, Zourla AP, Peros G and Karakitsos P. Simultaneous occurrence of Warthin-like papillary carcinoma and lymphoma of the mucosa associated lymphoid tissue in Hashimoto thyroiditis. J Clin Pathol 2010; 63: 662-663
- Paliogiannis P, Attene F, Trogu F and Trignano M. Warthin-like papillary carcinoma of the thyroid gland: case report and review of the literature. Case Rep Oncol Med 2012; 2012: 689291.
- Ersen A, Durak MG, Canda T, Sevinc AI, Saydam S and Kocdor MA. Warthin-like papillary carcinoma of the thyroid: a case series and review of the literature. Turk Patoloji Derg 2013; 29: 150-155.
Corresponding Author
Dr Sheela KM
Associate Professor (CAP), Department of Pathology, Govt. Medical College, Trivandrum
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.26
