Title: Diagnostic Evaluation of Ocular Surface Disease Index Questionnaire for Dry Eye Diseases

Authors: Anjana Nair S, V Sahasranamam, Susan Thomas, Karthik Raj Prabhakar

 DOI: https://dx.doi.org/10.18535/jmscr/v6i11.143

Abstract

Purpose: To find out whether subjective evaluation of dry eye with OSDI questionnaire correlates with clinical tests of dry eye

Method: 111 patients between 30 & 60 years of age, coming to OPD of a tertiary care centre with symptoms of dry eye were taken for the study. The study subjects were made to fill up the OSDI questionnaire and the tear film of same subjects were analysed with schirmer tests & TBUT. People who had previous ocular surgeries or having acute or chronic ocular surface abnormalities were excluded. Tools used are validated OSDI questionnaire, schirmer strips, fluorescein strips and slit lamp. Data were entered in Microsoft excel data sheets and analysed using SPSS 16.

Results: Out of 73 patients who had dry eye (low schirmer and TBUT values) 71patients (97.26%) were having OSDI scores suggestive of dry eye. Among those 71 patients, 27 patients had severe dry eye scores (37 %), 22 had moderate scores (30.1 %) and 22 had mild scores (30.1 %). Out of 38 patients who did not have dry eye, 20 patients had OSDI scores suggestive of dry eye and among those 20; 9(23.7 %), 9(23.7%) & 2(5.3 %) had mild, moderate & severe OSDI scores respectively.

Conclusion: The sensitivity of OSDI Questionnaire as per this study is 97.26% in detecting dry eye. But the specificity of test is only 47.37%. The questionnaire can be used as screening tool for dry eye diseases.

Keywords: dry eye disease; tear film evaluation; OSDI Questionnaire; OSDI score.

References

  1. Lin H, Yiu SC. Dry eye disease: A review of diagnostic approaches and treatments. Saudi J Ophthalmol. 2014 Jul;28(3):173–81.
  2. Amparo F, Schaumberg DA, Dana R. Comparison of Two Questionnaires for Dry Eye Symptom Assessment: The Ocular Surface Disease Index and the Symptom Assessment in Dry Eye. 2015 Jul;122(7):1498–503.
  3. Guo Y, Peng R, Feng K, Hong J. Diagnostic Performance of McMonnies Questionnaire as a Screening Survey for Dry Eye: A Multicenter Analysis [Internet]. Journal of Ophthalmology. 2016
  4. Milner MS, Beckman KA, Luchs JI, Allen QB, Awdeh RM, Berdahl J, et al. Dysfunctional tear syndrome: dry eye disease and associated tear film disorders – new strategies for diagnosis and treatment. Curr Opin Ophthalmol. 2017 Jan;28(Suppl 1):3–47.
  5. Valim V, Trevisani VFM, Sousa JM de, Vilela VS, Belfort R. Current Approach to Dry Eye Disease. Clin Rev Allergy Immunol. 2015 Dec 1;49(3):288–97.
  6. Nebbioso M, Del Regno P, Gharbiya M, Sacchetti M, Plateroti R, Lambiase A. Analysis of the Pathogenic Factors and Management of Dry Eye in Ocular Surface Disorders. Int J Mol Sci. 2017 Aug 13;18(8):1764.
  7. Ahn JM, Lee SH, Rim THT, Park RJ, Yang HS, Kim T im, et al. Prevalence of and Risk Factors Associated With Dry Eye: The Korea National Health and Nutrition Examination Survey 2010–2011. Am J Ophthalmol. 2014 Dec 1;158(6):1205–1214.e7.
  8. Peck T, Olsakovsky L, Aggarwal S. Dry Eye Syndrome in Menopause and Perimenop-ausal Age Group. J -Life Health. 2017;8(2):51–4.
  9. Lin P-Y, Tsai S-Y, Cheng C-Y, Liu J-H, Chou P, Hsu W-M. Prevalence of dry eye among an elderly Chinese population in Taiwan. 2003 Jun 1;110(6):1096–101.
  10. Ismailova DS, Fedorov AA, Grusha YO. Ocular Surface Changes in Thyroid Eye Disease. 2013 Apr 1;32(2):87–90.
  11. Bruscolini A, Abbouda A, Locuratolo N, Restivo L, Trimboli P, Romanelli F. Dry Eye Syndrome in Non-Exophthalmic Graves’ Disease. Semin Ophthalmol. 2015 Nov 2;30(5–6):372–6.
  12. Koca G, Acar U, Atilgan HI, Acar DE, Altiparmak UE, Demirel K, et al. Changes in conjunctival cytology and tear function tests with radioiodine treatment for hyperthyroidism. Ann Nucl Med. 2013 Oct 1;27(8):694–9.
  13. Zhang X, Zhao L, Deng S, Sun X, Wang N. Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics [Internet].
  14. DeMill DL, Hussain M, Pop-Busui R, Shtein RM. Ocular Surface Disease in Patients with Diabetic Peripheral Neuropathy. Br J Ophthalmol. 2016 Jul;100(7):924–8.
  15. Erdur SK, Aydin R, Ozsutcu M, Olmuscelik O, Eliacik M, Demirci G, et al. The Relationship between Metabolic Syndrome, Its Components, and Dry Eye: A Cross-Sectional Study. Curr Eye Res. 2017 Aug 3;42(8):1115–7.
  16. Li W, Graham AD, Lin MC. Understanding Ocular Discomfort and Dryness Using the Pain Sensitivity Questionnaire. PloS One. 2016;11(5):e0154753.
  17. Alves M, Reinach PS, Paula JS, Cruz AAV e, Bachette L, Faustino J, et al. Comparison of Diagnostic Tests in Distinct Well-Defined Conditions Related to Dry Eye Disease. PLOS ONE. 2014 May 21;9(5):e97921.
  18. Asiedu K, Kyei S, Mensah SN, Ocansey S, Abu LS, Kyere EA. Ocular Surface Disease Index (osdi) Versus the Standard Patient Evaluation of Eye Dryness (speed): A Study of a Nonclinical Sample. 2016 Feb 1;35(2):175–80.

Corresponding Author

V Sahasranamam

Director, Regional Institute of Ophthalmology, Thiruvananthapuram-695001, India

Phone number: +91-9846020421, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.