Abstract
Objectives: This present study was to evaluate the pattern of antihypertensive drug distribution as monotherapy, combination therapy and fixed dose combination of patients with hypertensive diabetes mellitus.
Methodology: A total of 100 patients of hypertensive diabetes mellitus were enrolled in this study. A detail history, complete assessment and relevant investigation were taken to all patients. Pattern of drug prescription was monotherapy, combination therapy and fixed dose combination.
Results: Data was analyzed by using simple statistical methods with the help of MS-Office software.
Conclusions: Patients of hypertensive diabetes mellitus was commonly seen in beyond 4th decades of life. Calcium channel blockers (amlodipine) and ACE inhibitors (Enalapril, ramipiril, lisinopril, levipril) were greatly prescribed in patients of hypertensive diabetes mellitus as monotherapy. AT II blocker with diuretics, ACE inhibitors with diuretics and β blocker with Calcium channel blocker were commonly used as combination therapy. And as a fixed dose combination therapy calcium channel blockers with angiotensine II receptor blocker and β blockers with diuretics were prescribed in majorities of patients with hypertensive diabetes mellitus. In mild to moderate HTN, the first line of treatment was lifestyle modification, i.e., weight control, low fat anti-atherogenic diet, salt restriction, reduction in alcohol intake, discontinuation of smoking, and some regimens of physical activity.
Keywords: Hypertension, Hypertensive diabetes mellitus, Antihypertensive drug prescription.
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Corresponding Author
Dr Yasmin Sultana Rahman
Post Graduate Trainee, Department of Pharmacology, Katihar Medical College, Katihar, Bihar, India
Ph: +91 8002736323, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i11.135
