Abstract

A 40-year-old lady with a history of Abnormal Uterine Bleeding (AUB) was prescribed Ormeloxifene, at a dosage of 60 mg once in 3 days for a period of 3 months following a fractional curettage. Subsequently the patient had taken hormonal analogues over a long period of time without a proper follow up. Later due to a persistent and intermittent Abnormal Uterine Bleeding (AUB), she approached the hospital again and a planned hysterectomy was done. The hysterectomy specimen exhibited simple endometrial hyperplasia with focal sessile endometrial polyps. The myometrium was hypertrophic and hyperplastic in nature, simulating the pregnancy changes with multiple foci of adenomyosis (florid adenomyosis). The right side fallopian tube also showed endometriosis. This case is being presented to stress the fact that whenever a patient is under a hormonal therapy for AUB, proper follow up should be done to look for endometrial changes via noninvasive ultrasonography and if any unusual findings are found, an endometrial biopsy should be done to rule out any changes.

Keywords: Ormeloxifene, Pregnancy changes, Endometrialpolyp, Endometrial hyperplasia, Florid adenomyosis, Endometriosis of Right Fallopian tube.